Toward revealing unknown biological functions: Approach from dynamism of drugs

In this post-genomic age, primary structures of receptors for transmitters and hormones have been revealed. One of the most important issues is the process through which the activation of receptors on cellular membrane triggers distinctive responses in the cells, i.e., intracellular signal transmission. The goal of our laboratory is to reveal how transmitters and drugs cause cellular responses by analyzing pharmacological responses from whole animals to cellular or molecular levels.


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