My research interest is to extract biological information from genome sequences. Recent research contents are evolutionary analyses of genomes of organisms such as humans through comparative genomics. I'm also interested in applied genomics, studying the genomes of infectious viruses aiming at the application for treatment through collaborative works. For example, in collaboration with researchers from the school of Medicine, we are trying to reveal how novel types of adenoviruses, which cause epidemic keratoconjunctivitis, have emerged and which parts of their genomes are responsible for infection. Also, we are studying how genomes of rice tungro bacilliform virus and its host rice have evolved with researchers from the school of Agriculture. My research goal is to reveal how genomes are related to phenotypes and how genomes brought biodiversity and evolution of organisms based on genome informatics.

1. Teaching information science to graduate students

1. Yamada A, Koyanagi KO, Watanabe H. (2011) In silico and in vivo identification of the intermediate filament vimentin that is downregulated downstream of Brachyury during Xenopus embryogenesis. Gene 491(2):232-6..
2. Kaneko H, Aoki K, Ishida S, Ohno S, Kitaichi N, Ishiko H, Fujimoto T, Ikeda Y, Nakamura M, Gonzalez G, Koyanagi KO, Watanabe H, Suzutani T. (2011) Recombination analysis of intermediate human adenovirus type 53 in Japan by complete genome sequence. J. Gen. Virol. 92:1251-9.
3. Kaneko H, Aoki K, Ohno S, Ishiko H, Fujimoto T, Kikuchi M, Harada S, Gonzalez G, Koyanagi KO, Watanabe H, Suzutani T. (2011) Complete genome analysis of a novel intertypic recombinant human adenovirus causing epidemic keratoconjunctivitis in Japan. J. Clin. Microbiol. 49(2):484-90.
4. Tanaka T, Koyanagi KO, Itoh T. (2009) Highly diversified molecular evolution of downstream transcription start sites in rice and Arabidopsis. Plant Physiology 149(3):1316-1324
5. Koyanagi KO, Imanishi T, Gojobori T. (2008) Bidirectional Gene Pairs in the Human Genome. ENCYCLOPEDIA OF LIFE SCIENCES DOI: 10.1002/9780470015902.a0020776