研究業績

2026年

1. Batchuluun Enkhtuul, Ochirbat Khurtsbaatar, Baasansuren Lkham, Tumurtogtokh Agiimaa, Jugderkhorloo Unenbat, Burenbaatar Buyanbadrakh, Sugir Ninjbulgan, Borjigin Liushiqi, Yasuhiko Suzuki, Takashi Kimura, Vanaabaatar Batbaatar. Re-emergence of equine glanders in Mongolia based on region-wide serosurveillance.. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 38(3), 505-508, 2026. doi: 10.1177/10406387261422668
2. Ai Koshikawa, Yoshiki Ichikawa, Mitsuru Nakase, Apichai Tuanyok, Vannarat Saechan, Keisuke Aoshima, Hideaki Higashi, Chie Nakajima, Yasuhiko Suzuki, Vanaabaatar Batbaatar, Takashi Kimura. Development of a Novel Real-Time PCR Assay Differentiating Burkholderia mallei From Burkholderia pseudomallei.. Microbiology and immunology, 2026. doi: 10.1111/1348-0421.70061
3. Tamami Suzuki, Rieru Kiyama, Paul Dela Cruz Valcorza, Keisuke Aoshima, Takashi Kimura. An exophytic multinodular chordoma of the cervical spine in a ferret.. Journal of toxicologic pathology, 39(2), 87-92, 2026. doi: 10.1293/tox.2025-0102
4. Otgontuya Ganbaatar, Vanaabaatar Batbaatar, Takashi Kimura, Sumiya Ganzorig, Erdene-Ochir Tseren-Ochir, Yasunori Suzuki, Shinji Takai. Seroepidemiological survey of Rhodococcus equi infection in adult horses in Mongolia.. The Journal of veterinary medical science, 88(3), 482-484, 2026. doi: 10.1292/jvms.25-0393
5. Mariko Miki, Yo Shimazu, Ryo Daniel Obara, Takashi Nagamine, Yumiko Nakaya, Yoshinori Ikenaka, Hiromi Osaki, Takashi Kimura, Takahiro Hiono, Norikazu Isoda, Takao Shishido, Yoshihiro Sakoda. Assessment of a baloxavir marboxil treatment protocol for high pathogenicity avian influenza in Okinawa Rails, an endangered species endemic to Japan.. PloS one, 21(3), e0345055, 2026. doi: 10.1371/journal.pone.0345055

2025年

1. 市川 世識, 鈴木 玲海, Pau Valcorza, 後藤 拓磨, 古田 若葉, 日尾野 隆大, 直 亨則, 佐藤 豊孝, 池中 良徳, 石塚 真由美, 青島 圭佑, 木村 享史. 国内におけるカラスオルソレオウイルスによるカラス大量死事例. 北海道獣医師会雑誌, 69(8), 374, 2025.
2. 加藤 史, 笹岡 一慶, 新坊 弦也, 越川 藍, 木村 享史, 滝口 満喜. 行動異常を主訴としたフレンチブルドッグの大脳膠腫症の1例. 北海道獣医師会雑誌, 69(8), 355, 2025.
3. Yoshiki Ichikawa, Yukiko Iinuma, Tomohiro Okagawa, Ryo Shimbo, Batchuluun Enkhtuul, Ochirbat Khurtsbaatar, Yuta Kinoshita, Hidekazu Niwa, Keisuke Aoshima, Atsushi Kobayashi, Vanaabaatar Batbaatar, Kazuhiko Ohashi, Takashi Kimura. Comparison of immunogenicity of 17 Burkholderia mallei antigens and whole cell lysate using indirect ELISA.. The Journal of veterinary medical science, 87(4), 394-401, 2025. doi: 10.1292/jvms.25-0039
4. Mitsuru Nakase, Jeewan Thapa, Vanaabaatar Batbaatar, Ochirbat Khurtsbaatar, Batchuluun Enkhtuul, Jugderkhorloo Unenbat, Baasansuren Lkham, Sachiho Fujita, Ai Koshikawa, Apichai Tuanyok, Vannarat Saechan, Hideaki Higashi, Kyoko Hayashida, Yasuhiko Suzuki, Chie Nakajima, Takashi Kimura. A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei.. BMC microbiology, 25(1), 36, 2025. doi: 10.1186/s12866-024-03737-z

2024年

1. Tamami Suzuki, Jumpei Yamazaki, Kouta Yamaguchi, Keisuke Aoshima, Takashi Kimura. Nodal T-cell lymphoma with eosinophilic infiltration and sclerosing fibroplasia in a cat with eosinophilia.. The Journal of veterinary medical science, 86(12), 1252-1255, 2024. doi: 10.1292/jvms.24-0225
2. Kittiya Intaruck, Koshiro Tabata, Yukari Itakura, Nijiho Kawaguchi, Mai Kishimoto, Agus Setiyono, Ekowati Handharyani, Hayato Harima, Takashi Kimura, William W Hall, Yasuko Orba, Hirofumi Sawa, Michihito Sasaki. Characterization of a mammalian orthoreovirus isolated from the large flying fox, Pteropus vampyrus, in Indonesia.. The Journal of general virology, 105(9), 2024. doi: 10.1099/jgv.0.002028
3. Yoshiki Ichikawa, Liushiqi Borjigin, Batchuluun Enkhtuul, Ochirbat Khurtsbaatar, Keisuke Aoshima, Atsushi Kobayashi, Vanaabaatar Batbaatar, Takashi Kimura. First molecular characterization of Burkholderia mallei strains isolated from horses in Mongolia. Infection, Genetics and Evolution, 123, 105616, 2024. doi: 10.1016/j.meegid.2024.105616
4. Mayuko Maeda, Miou Abe, Keisuke Aoshima, Atsushi Kobayashi, Hideto Fukushi, Takashi Kimura. Identification of the Promoter Antisense Transcript Enhancing the Transcription of the Equine Herpesvirus-1 Immediate-Early Gene.. Viruses, 16(8), 2024. doi: 10.3390/v16081195
5. Miki M, Obara RD, Nishimura K, Shishido T, Ikenaka Y, Oka R, Sato K, Nakayama SMM, Takashi Kimura, Kobayashi A, Aoshima K, Saito K, Hiono T, Isoda N, Sakoda Y. FOUR-WEEK ORAL ADMINISTRATION OF BALOXAVIR MARBOXIL AS AN ANTI-INFLUENZA VIRUS DRUG SHOWS NO TOXICITY IN CHICKENS. J Zoo Wildl Med, 55(2), 313-321, 2024. doi: 10.1638/2023-0103

2023年

1. Kobayashi A, Hirata T, Shimazaki T, Munesue Y, Aoshima K, Takashi Kimura, Nio-Kobayashi J, Hasebe R, Takeuchi A, Matsuura Y, Kusumi S, Koga D, Iwasaki Y, Kinoshita T, Mohri S, Kitamoto T. A point mutation in GPI-attachment signal peptide accelerates the development of prion disease. Acta Neuropathol, 145(5), 637-650, 2023. doi: 10.1007/s00401-023-02553-5
2. Takahiro Hiono, Daiki Kobayashi, Atsushi Kobayashi, Tamami Suzuki, Yuki Satake, Rio Harada, Keita Matsuno, Mariko Sashika, Hinako Ban, Maya Kobayashi, Keisuke Aoshima, Fumihito Takaya, Hiroko Fujita, Norikazu Isoda, Takashi Kimura, Yoshihiro Sakoda. Virological, pathological, and glycovirological investigations of an Ezo red fox and a tanuki naturally infected with H5N1 highly pathogenic avian influenza viruses in Hokkaido, Japan. Virology, 578, 35-44, 2023. doi: 10.1016/j.virol.2022.11.008

2022年

1. Anri Hirai, Ryo Yamazaki, Atsushi Kobayashi, Takashi Kimura, Kei Nomiyama, Shuichi Shimma, Shouta M M Nakayama, Mayumi Ishizuka, Yoshinori Ikenaka. Detection of Changes in Monoamine Neurotransmitters by the Neonicotinoid Pesticide Imidacloprid Using Mass Spectrometry.. Toxics, 10(11), 2022. doi: 10.3390/toxics10110696
2. Kittiya Intaruck, Yukari Itakura, Mai Kishimoto, Herman M Chambaro, Agus Setiyono, Ekowati Handharyani, Kentaro Uemura, Hayato Harima, Satoshi Taniguchi, Masayuki Saijo, Takashi Kimura, Yasuko Orba, Hirofumi Sawa, Michihito Sasaki. Isolation and characterization of an orthoreovirus from Indonesian fruit bats.. Virology, 575, 10-19, 2022. doi: 10.1016/j.virol.2022.08.003
3. Hiroshi Sato, Chihiro Ishii, Shouta M M Nakayama, Takahiro Ichise, Keisuke Saito, Yukiko Watanabe, Kohei Ogasawara, Ryota Torimoto, Atsushi Kobayashi, Takashi Kimura, Yukiko Nakamura, Junya Yamagishi, Yoshinori Ikenaka, Mayumi Ishizuka. Behavior and toxic effects of Pb in a waterfowl model with oral exposure to Pb shots: Investigating Pb exposure in wild birds.. Environmental pollution (Barking, Essex : 1987), 119580, 2022. doi: 10.1016/j.envpol.2022.119580
4. 平井 杏梨, 山崎 凌, 小林 篤史, 木村 享史, 野見山 桂, 新間 秀一, 中山 翔太, 石塚 真由美, 池中 良徳. 質量分析を用いたモノアミン神経伝達物質の高感度検出(Sensitive Detection of Monoamine Neurotransmitters Using Mass Spectrometry). The Journal of Toxicological Sciences, 47(Suppl.), S141, 2022.
5. Tamami Suzuki, Keisuke Aoshima, Jumpei Yamazaki, Atsushi Kobayashi, Takashi Kimura. Manipulating Histone Acetylation Leads to Antitumor Effects in Hemangiosarcoma Cells.. Veterinary and comparative oncology, 20(4), 805-816, 2022. doi: 10.1111/vco.12840
6. Dai HASEGAWA, Keisuke AOSHIMA, Kazuyoshi SASAOKA, Atsushi KOBAYASHI, Mitsuyoshi TAKIGUCHI, Takashi Kimura. Malignant oligoastrocytoma in the spinal cord of a cat. Journal of Veterinary Medical Science, 84(9), 1277-1282, 2022. doi: 10.1292/jvms.22-0144

2021年

1. Atsushi Kobayashi, Yoshiko Munesue, Taishi Shimazaki, Keisuke Aoshima, Takashi Kimura, Shirou Mohri, Tetsuyuki Kitamoto. Potential for transmission of sporadic Creutzfeldt–Jakob disease through peripheral routes. Laboratory Investigation, 101(10), 1327-1330, 2021. doi: 10.1038/s41374-021-00641-2
2. Sittinee Kulprasertsri, Shintaro Kobayashi, Keisuke Aoshima, Atsushi Kobayashi, Takashi Kimura. Duck Tembusu virus induces stronger cellular responses than Japanese encephalitis virus in primary duck neurons and fibroblasts. Microbiology and Immunology, 65(11), 481-491, 2021. doi: 10.1111/1348-0421.12933
3. Yoshiki Ichikawa, Mizuki Heishima, Kristin Vyhnal, Keisuke Aoshima, Kazuyoshi Sasaoka, Ryohei Kinoshita, Atsushi Kobayashi, Mitsuyoshi Takiguchi, Takashi Kimura. Systemic mucoid degeneration of the arterial tunica intima in a young dog. Journal of Veterinary Diagnostic Investigation, 34(1), 104063872110425, 2021. doi: 10.1177/10406387211042587
4. Ryouta Torimoto, Chihiro Ishii, Hiroshi Sato, Keisuke Saito, Yukiko Watanabe, Kohei Ogasawara, Ayano Kubota, Takehisa Matsukawa, Kazuhito Yokoyama, Atsushi Kobayashi, Takashi Kimura, Shouta M.M. Nakayama, Yoshinori Ikenaka, Mayumi Ishizuka. Analysis of lead distribution in avian organs by LA-ICP-MS: Study of experimentally lead-exposed ducks and kites. Environmental Pollution, 283, 117086, 2021. doi: 10.1016/j.envpol.2021.117086
5. Kevin Christian Montecillo Gulay, Noriyuki Nagata, Keisuke Aoshima, Nozomi Shiohara, Atsushi Kobayashi, Mitsuyoshi Takiguchi, Takashi Kimura. Peliosis Hepatis with Chylous Ascites in a Dog. Journal of Comparative Pathology, 187, 63-67, 2021. doi: 10.1016/j.jcpa.2021.07.001
6. Kevin Christian Montecillo Gulay, Keisuke Aoshima, Yuki Shibata, Hironobu Yasui, Qin Yan, Atsushi Kobayashi, Takashi Kimura. KDM2B promotes cell viability by enhancing DNA damage response in canine hemangiosarcoma. Journal of Genetics and Genomics, 48(7), 618-630, 2021. doi: 10.1016/j.jgg.2021.02.005
7. Sittinee KULPRASERTSRI, Keisuke AOSHIMA, Atsushi KOBAYASHI, Takashi Kimura. Minocycline prevents primary duck neurons from duck Tembusu virus-induced death. Journal of Veterinary Medical Science, 83(4), 734-741, 2021. doi: 10.1292/jvms.20-0735

2020年

1. Teita Ishizaki, Jumpei Yamazaki, Shinji Meagawa, Nozomu Yokoyama, Keisuke Aoshima, Mitsuyoshi Takiguchi, Takashi Kimura. Long interspersed nucleotide element‐1 hypomethylation in canine malignant mucosal melanoma. Veterinary and Comparative Oncology, 18(4), 854-860, 2020. doi: 10.1111/vco.12591
2. Ochbayar Erdemsurakh, Baatarjargal Purevdorj, Khurtsbaatar Ochirbat, Altanchimeg Adilbish, Batbaatar Vanaabaatar, Keisuke Aoshima, Atsushi Kobayashi, Takashi Kimura. Pathological and Immunohistochemical Analyses of Naturally Occurring Equine Glanders Using an Anti-BpaB Antibody. Veterinary Pathology, 57(6), 807-811, 2020. doi: 10.1177/0300985820953422
3. Lesa A. Thompson, Atsuya Morita, Shoko Murakami, Noboru Sasaki, Miou Murashita, Ryou Yamazaki, Atsushi Kobayashi, Takashi Kimura, Mitsuyoshi Takiguchi. Wobbly hedgehog syndrome with disseminated histiocytic sarcoma and lateral ventricular meningioma in an African pygmy hedgehog. J Vet Diagn Invest, 32(6), 953-956, 2020. doi: 10.1177/1040638720958767
4. T. Ishizaki, J. Yamazaki, J. Jelinek, K. Aoshima, Takashi Kimura. Genome-wide DNA methylation analysis identifies promoter hypermethylation in canine malignant melanoma. Research in Veterinary Science, 132, 521-526, 2020. doi: 10.1016/j.rvsc.2020.08.006
5. Minato E, Kobayashi A, Aoshima K, Fukushi H, Takashi Kimura. Susceptibility of rat immortalized neuronal cell line Rn33B to equine herpesvirus-1 infection is differentiation-dependent. Microbiol Immunol, 64(2), 123-132, 2020. doi: 10.1111/1348-0421.12761
6. Ochbayar ERDEMSURAKH, Khurtsbaatar OCHIRBAT, Ulziisaikhan GOMBOSUREN, Batbold TSERENDORJ, Baatarjargal PUREVDORJ, Batbaatar VANAABAATAR, Keisuke AOSHIMA, Atsushi KOBAYASHI, Takashi Kimura. Seroprevalence of equine glanders in horses in the central and eastern parts of Mongolia. Journal of Veterinary Medical Science, 82(9), 1247-1252, 2020. doi: 10.1292/jvms.20-0219

2019年

1. Atsuya Morita, Keisuke Aoshima, Kevin Christian Montecillo Gulay, Shinichi Onishi, Yuki Shibata, Hironobu Yasui, Atsushi Kobayashi, Takashi Kimura. High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.. Research in veterinary science, 127, 1-10, 2019. doi: 10.1016/j.rvsc.2019.09.011
2. Minato E, Aoshima K, Kobayashi A, Ohnishi N, Sasaki N, Takashi Kimura. Exogenous Expression of Equine MHC Class I Molecules in Mice Increases Susceptibility to Equine Herpesvirus 1 Pulmonary Infection.. Veterinary pathology, 56(5), 703-710, 2019. doi: 10.1177/0300985819834616
3. Kobayashi A, Iwasaki Y, Takao M, Saito Y, Iwaki T, Qi Z, Torimoto R, Shimazaki T, Munesue Y, Isoda N, Sawa H, Aoshima K, Takashi Kimura, Kondo H, Mohri S, Kitamoto T. A novel combination of prion strain co-occurrence in patients with sporadic Creutzfeldt-Jakob disease.. The American journal of pathology, 189(6), 1276-1283, 2019. doi: 10.1016/j.ajpath.2019.02.012
4. Kobayashi A, Qi Z, Shimazaki T, Munesue Y, Miyamoto T, Isoda N, Sawa H, Aoshima K, Takashi Kimura, Mohri S, Kitamoto T, Yamashita T, Miyoshi I. Ganglioside synthase knock-out reduces prion disease incubation time in mouse models.. The American journal of pathology, 189(3), 677-686, 2019. doi: 10.1016/j.ajpath.2018.11.009
5. Hiroko Oshima, Sau-Yee Kok, Mizuho Nakayama, Kazuhiro Murakami, Dominic Chih-Cheng Voon, Takashi Kimura, Masanobu Oshima. Stat3 is indispensable for damage‐induced crypt regeneration but not for Wnt‐driven intestinal tumorigenesis. The FASEB Journal, 33(2), 1873-1886, 2019. doi: 10.1096/fj.201801176r

2018年

1. Keisuke Aoshima, Yuki Fukui, Kevin Christian Montecillo Gulay, Ochbayar Erdemsurakh, Atsuya Morita, Atsushi Kobayashi, Takashi Kimura. Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells. BMC Veterinary Research, 14(1), 301, 2018. doi: 10.1186/s12917-018-1624-8
2. Shimamoto Y, Nio-Kobayashi J, Watarai H, Nagano M, Saito N, Takahashi E, Higuchi H, Kobayashi A, Takashi Kimura, Kitamura H. Generation and validation of novel anti-bovine CD163 monoclonal antibodies ABM-1A9 and ABM-2D6. Vet Immunol Immunopathol, 198, 6-13, 2018. doi: 10.1016/j.vetimm.2018.02.004
3. Wada Y, Sasaki M, Setiyono A, Handharyani E, Rahmadani I, Taha S, Adiani S, Latief M, Kholilullah ZA, Subangkit M, Kobayashi S, Nakamura I, Takashi Kimura, Orba Y, Sawa H. Detection of novel gammaherpesviruses from fruit bats in Indonesia.. Journal of medical microbiology, 67(3), 415-422, 2018. doi: 10.1099/jmm.0.000689
4. Munesue Y, Shimazaki T, Qi Z, Isoda N, Sawa H, Aoshima K, Takashi Kimura, Mohri S, Kitamoto T, Kobayashi A. Development of a quick bioassay for the evaluation of transmission properties of acquired prion diseases.. Neuroscience letters, 668, 43-47, 2018. doi: 10.1016/j.neulet.2018.01.014
5. K.E. Mwape, V.C. Zulu, I.K. Phiri, J. Yabe, N. Nishida, K. Aoshima, Y. Qiu, Takashi Kimura, G.S. Pandey. A large osteosarcoma in the mandible of an ox. Indian Journal of Veterinary Pathology, 42(2), 119, 2018. doi: 10.5958/0973-970x.2018.00023.8
6. Aprilia MAHARANI, Keisuke AOSHIMA, Shinichi ONISHI, Kevin Christian Montecillo GULAY, Atsushi KOBAYASHI, Takashi Kimura. Cellular atypia is negatively correlated with immunohistochemical reactivity of CD31 and vWF expression levels in canine hemangiosarcoma.. The Journal of veterinary medical science, 80(2), 213-218, 2018. doi: 10.1292/jvms.17-0561
7. Rahpaya SS, Tsuchiaka S, Kishimoto M, Oba M, Katayama Y, Nunomura Y, Kokawa S, Takashi Kimura, Kobayashi A, Kirino Y, Okabayashi T, Nonaka N, Mekata H, Aoki H, Shiokawa M, Umetsu M, Morita T, Hasebe A, Otsu K, Asai T, Yamaguchi T, Makino S, Murata Y, Abi AJ, Omatsu T, Mizutani T. Dembo-PCR technique for the detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs. J Vet Sci, 19(3), 350, 2018. doi: 10.4142/jvs.2018.19.3.350

2017年

1. Nguyen LT, Nakaishi K, Motojima K, Ohkawara A, Minato E, Maruyama J, Hiono T, Matsuno K, Okamatsu M, Takashi Kimura, Takada A, Kida H, Sakoda Y. Rapid and broad detection of H5 hemagglutinin by an immunochromatographic kit using novel monoclonal antibody against highly pathogenic avian influenza virus belonging to the genetic clade 2.3.4.4.. PloS one, 12(8), e0182228, 2017. doi: 10.1371/journal.pone.0182228
2. Satoko IZUME, Rikio KIRISAWA, Kenji OHYA, Aiko OHNUMA, Takashi Kimura, Tsutomu OMATSU, Yukie KATAYAMA, Tetsuya MIZUTANI, Hideto FUKUSHI. The full genome sequences of 8 equine herpesvirus type 4 isolates from horses in Japan. Journal of Veterinary Medical Science, 79(1), 206-212, 2017. doi: 10.1292/jvms.16-0506

2016年

1. Sasaki M, Gonzalez G, Wada Y, Setiyono A, Handharyani E, Rahmadani I, Taha S, Adiani S, Latief M, Kholilullah ZA, Subangkit M, Kobayashi S, Nakamura I, Takashi Kimura, Orba Y, Ito K, Sawa H. Divergent bufavirus harboured in megabats represents a new lineage of parvoviruses.. Scientific reports, 6(1), 24257, 2016. doi: 10.1038/srep24257

2015年

1. Anindita PD, Sasaki M, Setiyono A, Handharyani E, Orba Y, Kobayashi S, Rahmadani I, Taha S, Adiani S, Subangkit M, Nakamura I, Sawa H, Takashi Kimura. Detection of coronavirus genomes in Moluccan naked-backed fruit bats in Indonesia.. Archives of virology, 160(4), 1113-1118, 2015. doi: 10.1007/s00705-015-2342-1
2. Kobayashi S, Sasaki M, Nakao R, Setiyono A, Handharyani E, Orba Y, Rahmadani I, Taha S, Adiani S, Subangkit M, Nakamura I, Takashi Kimura, Sawa H. Detection of novel polyomaviruses in fruit bats in Indonesia.. Archives of virology, 160(4), 1075-1082, 2015. doi: 10.1007/s00705-015-2349-7

2014年

1. Kobayashi S, Orba Y, Yamaguchi H, Takahashi K, Sasaki M, Hasebe R, Takashi Kimura, Sawa H. Autophagy inhibits viral genome replication and gene expression stages in West Nile virus infection.. Virus research, 191, 83-91, 2014. doi: 10.1016/j.virusres.2014.07.016
2. Sasaki Michihito, Setiyono Agus, Handharyani Ekowati, Kobayashi Shintaro, Rahmadani Ibenu, Taha Siswatiana, Adiani Sri, Subangkit Mawar, Nakamura Ichiro, Sawa Hirofumi, Takashi Kimura. Isolation and characterization of a novel alphaherpesvirus in fruit bats.. Journal of virology, 88(17), 9819-9829, 2014. doi: 10.1128/jvi.01277-14
3. Yamaguchi H, Kobayashi S, Maruyama J, Sasaki M, Takada A, Takashi Kimura, Sawa H, Orba Y. Role of the C-terminal region of vervet monkey polyomavirus 1 VP1 in virion formation.. The Journal of veterinary medical science / the Japanese Society of Veterinary Science, 76(5), 637-644, 2014. doi: 10.1292/jvms.13-0568
4. Muleya W, Sasaki M, Orba Y, Ishii A, Thomas Y, Nakagawa E, Ogawa H, Hang'ombe B, Namangala B, Mweene A, Takada A, Takashi Kimura, Sawa H. Molecular epidemiology of paramyxoviruses in frugivorous Eidolon helvum bats in Zambia.. The Journal of veterinary medical science, 76(4), 611-614, 2014. doi: 10.1292/jvms.13-0518
5. Sasaki M, Muleya W, Ishii A, Orba Y, Hang'ombe BM, Mweene AS, Moonga L, Thomas Y, Takashi Kimura, Sawa H. Molecular epidemiology of paramyxoviruses in Zambian wild rodents and shrews.. The Journal of general virology, 95(2), 325-330, 2014. doi: 10.1099/vir.0.058404-0
6. Makino Y, Suzuki T, Hasebe R, Takashi Kimura, Maeda A, Takahashi H, Sawa H. Establishment of tracking system for West Nile virus entry and evidence of microtubule involvement in particle transport.. Journal of virological methods, 195, 250-257, 2014. doi: 10.1016/j.jviromet.2013.10.002
7. Xiaoqin Guo, Satoko Izume, Ayaka Okada, Kenji Ohya, Kenji Ohya, Takashi Kimura, Hideto Fukushi, Hideto Fukushi. Full genome sequences of zebra-borne equine herpesvirus type 1 isolated from zebra, Onager and Thomson’s gazelle. Journal of Veterinary Medical Science, 76(9), 1309-1312, 2014. doi: 10.1292/jvms.14-0183

2013年

1. Takashi Kimura, Okumura M, Kim E, Sasaki M, Orba Y, Sawa H. Characterization of Japanese encephalitis virus infection in an immortalized mesencephalic cell line, CSM14.1.. Microbiology and immunology, 57(10), 723-731, 2013. doi: 10.1111/1348-0421.12085
2. Hiroki Yamaguchi, Shintaro Kobayashi, Akihiro Ishii, Hirohito Ogawa, Ichiro Nakamura, Ladslav Moonga, Bernard M. Hang'ombe, Aaron S. Mweene, Yuka Thomas, Takashi Kimura, Hirofumi Sawa, Yasuko Orba. Identification of a novel polyomavirus from vervet monkeys in Zambia. Journal of General Virology, 94(6), 1357-1364, 2013. doi: 10.1099/vir.0.050740-0
3. Kobayashi S, Suzuki T, Igarashi M, Orba Y, Ohtake N, Nagakawa K, Niikura K, Takashi Kimura, Kasamatsu H, Sawa H. Cysteine residues in the major capsid protein, Vp1, of the JC virus are important for protein stability and oligomer formation.. PloS one, 8(10), e76668, 2013. doi: 10.1371/journal.pone.0076668
4. Muramatsu M, Yoshida R, Miyamoto H, Tomabechi D, Kajihara M, Maruyama J, Takashi Kimura, Manzoor R, Ito K, Takada A. Heterosubtypic antiviral activity of hemagglutinin-specific antibodies induced by intranasal immunization with inactivated influenza viruses in mice.. PloS one, 8(8), e71534, 2013. doi: 10.1371/journal.pone.0071534
5. Sasaki M, Ishii A, Orba Y, Thomas Y, Hang'ombe BM, Moonga L, Mweene AS, Ogawa H, Nakamura I, Takashi Kimura, Sawa H. Human parainfluenza virus type 3 in wild nonhuman primates, Zambia.. Emerging infectious diseases, 19(9), 1500-1503, 2013. doi: 10.3201/eid1909.121404

2012年

1. Walter Muleya, Boniface Namangala, Martin Simuunza, Ryo Nakao, Noboru Inoue, Takashi Kimura, Kimihito Ito, Chihiro Sugimoto, Hirofumi Sawa. Population genetic analysis and sub-structuring of Theileria parva in the northern and eastern parts of Zambia. PARASITES & VECTORS, 5, 255, 2012. doi: 10.1186/1756-3305-5-255
2. Michihito Sasaki, Agus Setiyono, Ekowati Handharyani, Ibenu Rahmadani, Siswatiana Taha, Sri Adiani, Mawar Subangkit, Hirofumi Sawa, Ichiro Nakamura, Takashi Kimura. Molecular detection of a novel paramyxovirus in fruit bats from Indonesia. VIROLOGY JOURNAL, 9, 240, 2012. doi: 10.1186/1743-422X-9-240
3. Kensuke Nakamura, Masahiro Yamasaki, Tomohiro Osaki, Hiroshi Ohta, Noboru Sasaki, Keisuke Aoshima, Takashi Kimura, Mitsuyoshi Takiguchi. Bilateral Segmental Aplasia with Unilateral Uterine Horn Torsion in a Pomeranian Bitch. JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 48(5), 327-330, 2012. doi: 10.5326/JAAHA-MS-5771
4. Nilton Akio Muto, Yuji Sunden, Tomoe Hattori, Daisuke Fujikura, Yosuke Nakayama, Tadaaki Miyazaki, Mitsuo Maruyama, Takashi Kimura, Hirofumi Sawa. Pathological Examination of Lung Tissues in Influenza A Virus-Infected Mice. JAPANESE JOURNAL OF INFECTIOUS DISEASES, 65(5), 383-391, 2012. doi: 10.7883/yoken.65.383
5. Tadaki Suzuki, Shingo Semba, Yuji Sunden, Yasuko Orba, Shintaro Kobayashi, Kazuo Nagashima, Takashi Kimura, Hideki Hasegawa, Hirofumi Sawa. Role of JC virus agnoprotein in virion formation. MICROBIOLOGY AND IMMUNOLOGY, 56(9), 639-646, 2012. doi: 10.1111/j.1348-0421.2012.00484.x
6. Shintaro Kobayashi, Yasuko Orba, Hiroki Yamaguchi, Takashi Kimura, Hirofumi Sawa. Accumulation of ubiquitinated proteins is related to West Nile virus-induced neuronal apoptosis. NEUROPATHOLOGY, 32(4), 398-405, 2012. doi: 10.1111/j.1440-1789.2011.01275.x
7. Nilton Akio Muto, Reiko Yoshida, Tadaki Suzuki, Shintaro Kobayashi, Hiroichi Ozaki, Daisuke Fujikura, Rashid Manzoor, Mieko Muramatsu, Ayato Takada, Takashi Kimura, Hirofumi Sawa. Inhibitory effects of an M2-specific monoclonal antibody on different strains of influenza A virus. JAPANESE JOURNAL OF VETERINARY RESEARCH, 60(2-3), 71-83, 2012.
8. Walter Muleya, Boniface Namangala, Aaron Mweene, Luke Zulu, Paul Fandamu, Douglas Banda, Takashi Kimura, Hirofumi Sawa, Akihiro Ishii. Molecular epidemiology and a loop-mediated isothermal amplification method for diagnosis of infection with rabies virus in Zambia. VIRUS RESEARCH, 163(1), 160-168, 2012. doi: 10.1016/j.virusres.2011.09.010

2011年

1. Michihito Sasaki, Eunmi Kim, Manabu Igarashi, Kimihito Ito, Rie Hasebe, Hideto Fukushi, Hirofumi Sawa, Takashi Kimura. Single Amino Acid Residue in the A2 Domain of Major Histocompatibility Complex Class I Is Involved in the Efficiency of Equine Herpesvirus-1 Entry. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(45), 39370-39378, 2011. doi: 10.1074/jbc.M111.251751
2. Jiancheng Chen, Shuhei Yamada, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashi, Kazuya I. P. J. Hidari, Takashi Suzuki, Yasuo Suzuki, Kazuyuki Sugahara. Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 412(1), 136-142, 2011. doi: 10.1016/j.bbrc.2011.07.059
3. Eunmi Kim, Megumi Okumura, Hirofumi Sawa, Tadaaki Miyazaki, Daisuke Fujikura, Shuhei Yamada, Kazuyuki Sugahara, Michihito Sasaki, Takashi Kimura. Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 409(4), 717-722, 2011. doi: 10.1016/j.bbrc.2011.05.072
4. Yasuko Orba, Shintaro Kobayashi, Ichiro Nakamura, Akihiro Ishii, Bernard M. Hang'ombe, Aaron S. Mweene, Yuka Thomas, Takashi Kimura, Hirofumi Sawa. Detection and characterization of a novel polyomavirus in wild rodents. JOURNAL OF GENERAL VIROLOGY, 92(4), 789-795, 2011. doi: 10.1099/vir.0.027854-0
5. Michihito Sasaki, Rie Hasebe, Yoshinori Makino, Tadaki Suzuki, Hideto Fukushi, Minoru Okamoto, Kazuya Matsuda, Hiroyuki Taniyama, Hirofumi Sawa, Takashi Kimura. Equine major histocompatibility complex class I molecules act as entry receptors that bind to equine herpesvirus-1 glycoprotein D. GENES TO CELLS, 16(4), 343-357, 2011. doi: 10.1111/j.1365-2443.2011.01491.x

2010年

1. Eunmi Kim, Megumi Okumura, Michihito Sasaki, Daisuke Fujikura, Tadaaki Miyazaki, Hirofumi Sawa, Takashi Kimura. Chondroitin sulfate-E induced enhancement of Japanese encephalitis virus infection. JOURNAL OF NEUROVIROLOGY, 16, 44, 2010.
2. Takashi Kimura, M. Sasaki, M. Okumura, E. Kim, H. Sawa. Flavivirus Encephalitis: Pathological Aspects of Mouse and Other Animal Models. VETERINARY PATHOLOGY, 47(5), 806-818, 2010. doi: 10.1177/0300985810372507
3. Akira Kawaguchi, Tadaki Suzuki, Takashi Kimura, Naoki Sakai, Tokiyoshi Ayabe, Hirofumi Sawa, Hideki Hasegawa. Functional analysis of an alpha-helical antimicrobial peptide derived from a novel mouse defensin-like gene. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 398(4), 778-784, 2010. doi: 10.1016/j.bbrc.2010.07.028
4. Tadaki Suzuki, Satoko Yamanouchi, Yuji Sunden, Yasuko Orba, Takashi Kimura, Hirofumi Sawa. Natalizumab Has No Direct Biological Effect on JC Virus Infectivity in Permissive Human Neural Cell Lines. JOURNAL OF MEDICAL VIROLOGY, 82(7), 1229-1235, 2010. doi: 10.1002/jmv.21805
5. Rie Hasebe, Tadaki Suzuki, Yoshinori Makino, Manabu Igarashi, Satoko Yamanouchi, Akihiko Maeda, Motohiro Horiuchi, Hirofumi Sawa, Takashi Kimura. Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein. BMC MICROBIOLOGY, 10, 165, 2010. doi: 10.1186/1471-2180-10-165
6. Tadaki Suzuki, Yasuko Orba, Yuki Okada, Yuji Sunden, Takashi Kimura, Shinya Tanaka, Kazuo Nagashima, William W. Hall, Hirofumi Sawa. The Human Polyoma JC Virus Agnoprotein Acts as a Viroporin. PLOS PATHOGENS, 6(3), e1000801, 2010. doi: 10.1371/journal.ppat.1000801
7. Yasuko Orba, Tadaki Suzuki, Yoshinori Makino, Kanako Kubota, Shinya Tanaka, Takashi Kimura, Hirofumi Sawa. Large T Antigen Promotes JC Virus Replication in G(2)-arrested Cells by Inducing ATM- and ATR-mediated G(2) Checkpoint Signaling. JOURNAL OF BIOLOGICAL CHEMISTRY, 285(2), 1544-1554, 2010. doi: 10.1074/jbc.M109.064311

2009年

1. Rie Hasebe, Michihito Sasaki, Hirofumi Sawa, Ryuichi Wada, Takashi Umemura, Takashi Kimura. Infectious entry of equine herpesvirus-1 into host cells through different endocytic pathways. VIROLOGY, 393(2), 198-209, 2009. doi: 10.1016/j.virol.2009.07.032
2. Akira Kawaguchi, Yasuko Orba, Takashi Kimura, Hidekatsu Iha, Masao Ogata, Takahiro Tsuji, Akira Ainai, Tetsutaro Sata, Takashi Okamoto, William W. Hall, Hirofumi Sawa, Hideki Hasegawa. Inhibition of the SDF-1 alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice. BLOOD, 114(14), 2961-2968, 2009. doi: 10.1182/blood-2008-11-189308

2008年

1. Yasuko Orba, Yuji Sunden, Tadaki Suzuki, Kazuo Nagashima, Takashi Kimura, Shinya Tanaka, Hirofumi Sawa. Pharmacological cdk inhibitor R-Roscovitine suppresses JC virus proliferation. VIROLOGY, 370(1), 173-183, 2008. doi: 10.1016/j.virol.2007.08.034

2006年

1. T Toyoda, K Ochiai, H Hatai, M Murakami, E Ono, Takashi Kimura, T Umemura. Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma. VETERINARY PATHOLOGY, 43(3), 294-301, 2006. doi: 10.1354/vp.43-3-294
2. R Hasebe, Takashi Kimura, K Nakamura, K Ochiai, K Okazaki, R Wada, T Umemura. Differential susceptibility of equine and mouse brain microvascular endothelial cells to equine herpesvirus 1 infection. ARCHIVES OF VIROLOGY, 151(4), 775-786, 2006. doi: 10.1007/s00705-005-0653-3
3. Shin, J, Sakoda, Y, Kim, J.-H, Tanaka, T, Kida, H, Takashi Kimura, Ochiai, K, Umemura, T. Efficacy of Intracerebral Immunization against Pseudorabies Virus in Mice. Microbiology and Immunology, 50, 823-830, 2006.

2005年

1. H Hatai, K Ochiai, Y Tomioka, T Toyoda, K Hayashi, M Anada, M Kato, A Toda, K Ohashi, E Ono, Takashi Kimura, T Umemura. Nested polymerase chain reaction for detection of the avian leukosis virus causing so-called fowl glioma. AVIAN PATHOLOGY, 34(6), 473-479, 2005. doi: 10.1080/03079450500368086
2. K Matsuda, T Shibata, Y Sakoda, H Kida, Takashi Kimura, K Ochiai, T Umemura. In vitro demonstration of neural transmission of avian influenza A virus. JOURNAL OF GENERAL VIROLOGY, 86(4), 1131-1139, 2005. doi: 10.1099/vir.0.80704-0
3. Matsuda K, Shibata T, Sakoda Y, Kida H, Takashi Kimura, Ochiai K, Umemura T. The vagus nerve is one route of transneural invasion for intranasally inoculated influenza A virus in mice. Journal of General Virology, 86, 1131-1139, 2005.
4. T Toyoda, K Ochiai, K Ohashi, Y Tomioka, Takashi Kimura, T Umemura. Multiple perineuriomas in chicken (Gallus gallus domesticus). VETERINARY PATHOLOGY, 42(2), 176-183, 2005. doi: 10.1354/vp.42-2-176

2004年

1. K Shirato, Takashi Kimura, T Mizutani, H Kariwa, Takashima, I. Different chemokine expression in lethal and non-lethal murine West Nile virus infection. JOURNAL OF MEDICAL VIROLOGY, 74(3), 507-513, 2004. doi: 10.1002/jmv.20205
2. K Watanabe, T Kadosawa, T Ishiguro, S Takagi, K Ochiai, Takashi Kimura, M Okumura, T Fujinaga. Odontogenic cysts in three dogs: One odontogenic keratocyst and two dentigerous cysts. JOURNAL OF VETERINARY MEDICAL SCIENCE, 66(9), 1167-1170, 2004. doi: 10.1292/jvms.66.1167
3. Y Tomioka, K Ochiai, K Ohashi, E Ono, T Toyoda, Takashi Kimura, T Umemura. Genome sequence analysis of the avian retrovirus causing so-called fowl glioma and the promoter activity of the long terminal repeat. JOURNAL OF GENERAL VIROLOGY, 85(3), 647-652, 2004. doi: 10.1099/vir.0.79778-0
4. K Matsuda, CH Park, Y Sunden, Takashi Kimura, K Ochiai, H Kida, T Umemura. The vagus nerve is one route of transneural invasion for intranasally inoculated influenza A virus in mice. VETERINARY PATHOLOGY, 41(2), 101-107, 2004. doi: 10.1354/vp.41-2-101
5. K Nakamura, K Ochiai, T Kadosawa, Takashi Kimura, T Umemura. Canine ganglioneuroblastoma in the oral mucosa. JOURNAL OF COMPARATIVE PATHOLOGY, 130(2-3), 205-208, 2004. doi: 10.1016/j.jcpa.2003.09.002
6. T Toyoda, K Ochiai, M Komatsu, Takashi Kimura, T Umemura. Nutritional secondary hyperparathyroidism and osteodystrophia fibrosa in a Hodgson's hawk-eagle (Spizaetus nipalensis). AVIAN PATHOLOGY, 33(1), 9-12, 2004. doi: 10.1080/03079450310001636237
7. Takashi Kimura, R Hasebe, R Mukaiya, K Ochiai, R Wada, T Umemura. Decreased expression of equine herpesvirus-1 early and late genes in the placenta of naturally aborted equine fetuses. JOURNAL OF COMPARATIVE PATHOLOGY, 130(1), 41-47, 2004. doi: 10.1016/S0021-9975(03)00068-9

2003年

1. Y Tomioka, K Ochiai, K Ohashi, Takashi Kimura, T Umemura. In ovo infection with an avian leukosis virus causing fowl glioma: viral distribution and pathogenesis. AVIAN PATHOLOGY, 32(6), 617-624, 2003. doi: 10.1080/03079450310001610640
2. CH Park, K Matsuda, Y Sunden, A Ninomiya, A Takada, H Ito, Takashi Kimura, K Ochiai, H Kida, T Umemura. Persistence of viral RNA segments in the central nervous system of mice after recovery from acute influenza A virus infection. VETERINARY MICROBIOLOGY, 97(3-4), 259-268, 2003. doi: 10.1016/j.vetmic.2003.10.001
3. Y Sunden, CH Park, K Matsuda, A Anagawa, Takashi Kimura, K Ochiai, H Kida, T Umemura. The effects of antipyretics on influenza virus encephalitis in mice and chicks. JOURNAL OF VETERINARY MEDICAL SCIENCE, 65(11), 1185-1188, 2003. doi: 10.1292/jvms.65.1185
4. Kim HO, Matsuda K, Takashi Kimura, Ochiai K, Yazawa H, Itakura C, Umemura T. Impaired myelinogenesis and early maturation of oligodendrocytes inblack tremor hamster with central nervous system myelin deficiency. Journal of Toxicological Pathology, 16, 209-213, 2003. doi: 10.1293/tox.16.209
5. T Mizutani, M Kobayashi, Y Eshita, K Shirato, Takashi Kimura, Y Ako, H Miyoshi, T Takasaki, Kurane, I, H Kariwa, T Umemura, Takashima, I. Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytosis, endocytosis and infection of West Nile virus. INSECT MOLECULAR BIOLOGY, 12(5), 491-499, 2003. doi: 10.1046/j.1365-2583.2003.00435.x
6. HO Kim, Takashi Kimura, K Ochiai, H Yazawa, C Itakura, T Umemura. Sustained hypomyelination and high serum thyroid hormone in aged black tremor hamster. JAPANESE JOURNAL OF VETERINARY RESEARCH, 51(2), 113-120, 2003. doi: 10.14943/jjvr.51.2.113
7. Takashi Kimura, DE Griffin. Extensive immune-mediated hippocampal damage in mice surviving infection with neuroadapted Sindbis virus. VIROLOGY, 311(1), 28-39, 2003. doi: 10.1016/0042-6822(03)00110-7

2002年

1. R Hasebe, Takashi Kimura, K Nakamura, K Okazaki, K Ochiai, R Wada, T Umemura. Passage of equine herpesvirus-1 in suckling mouse brain enhances extraneural virus growth and subsequent hematogenous neuroinvasion. JOURNAL OF VETERINARY MEDICAL SCIENCE, 64(10), 907-912, 2002. doi: 10.1292/jvms.64.907
2. A Kobayashi, S Katagiri, Takashi Kimura, K Ochiai, T Umemura. Steroid hormones do not reactivate Neospora caninum in ovariectomized mice. JOURNAL OF VETERINARY MEDICAL SCIENCE, 64(9), 773-777, 2002. doi: 10.1292/jvms.64.773
3. R Hasebe, Takashi Kimura, E Sato, K Okazaki, K Ochiai, R Wada, T Umemura. Equine herpesvirus-1-induced encephalomyelitis in mice: a comparative study of neuroadapted virus and its parental strain. JOURNAL OF COMPARATIVE PATHOLOGY, 127(2-3), 118-125, 2002. doi: 10.1053/jcpa.2002.0569
4. CH Park, M Ishinaka, A Takada, H Kida, Takashi Kimura, K Ochiai, T Umemura. The invasion routes of neurovirulent A Hong Kong 483/97 (H5N1) influenza virus into the central nervous system after respiratory infection in mice. ARCHIVES OF VIROLOGY, 147(7), 1425-1436, 2002. doi: 10.1007/s00705-004-0750-x

2001年

1. Takashi Kimura, Mitsui, I, Y Okada, T Furuya, K Ochiai, T Umemura, C Itakura. Distribution of rabbit haemorrhagic disease virus RNA in experimentally infected rabbits. JOURNAL OF COMPARATIVE PATHOLOGY, 124(2-3), 134-141, 2001. doi: 10.1053/jcpa.2000.0440
2. DE Griffin, S Ubol, P Despres, Takashi Kimura, A Byrnes. Role of antibodies in controlling alphavirus infection of neurons. ANTIBODIES IN VIRAL INFECTION, 260, 191-200, 2001.

2000年

1. R Mukaiya, Takashi Kimura, K Ochiai, R Wada, T Umemura. Demonstration of equine herpesvirus-1 gene expression in the placental trophoblasts of naturally aborted equine fetuses. JOURNAL OF COMPARATIVE PATHOLOGY, 123(2-3), 119-125, 2000. doi: 10.1053/jcpa.2000.0401
2. DC Thach, Takashi Kimura, DE Griffin. Differences between C57BL/6 and BALB/cBy mice in mortality and virus replication after intranasal infection with neuroadapted Sindbis virus. JOURNAL OF VIROLOGY, 74(13), 6156-6161, 2000. doi: 10.1128/JVI.74.13.6156-6161.2000
3. Takashi Kimura, DE Griffin. The role of CD8(+) T cells and major histocompatibility complex class I expression in the central nervous system of mice infected with neurovirulent Sindbis virus. JOURNAL OF VIROLOGY, 74(13), 6117-6125, 2000. doi: 10.1128/JVI.74.13.6117-6125.2000
4. T Watanabe, N Shinohara, A Sazawa, Y Kobayashi, Y Ogiso, Takashi Kimura, M Takiguchi, J Yasuda, A Hashimoto, T Koyanagi, N Kuzumaki. Suppressive effects of dominant negative ras mutant N116Y on transformed phenotypes of human bladder cancer cells. CANCER LETTERS, 149(1-2), 195-202, 2000. doi: 10.1016/S0304-3835(99)00359-6

1999年

1. Y Nishino, M Funaba, R Fukushima, T Mizutani, Takashi Kimura, R Iizuka, H Hirami, M Hara. Borna disease virus infection in domestic cats: Evaluation by RNA and antibody detection. JOURNAL OF VETERINARY MEDICAL SCIENCE, 61(10), 1167-1170, 1999. doi: 10.1292/jvms.61.1167
2. K Ochiai, Takashi Kimura, K Uematsu, T Umemura, C Itakura. Lead poisoning in wild waterfowl in Japan. JOURNAL OF WILDLIFE DISEASES, 35(4), 766-769, 1999.
3. E Handharyani, K Ochiai, T Kadosawa, Takashi Kimura, T Umemura. Canine hemangiopericytoma: an evaluation of metastatic potential. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 11(5), 474-478, 1999.
4. E Hayashida, K Ochiai, T Kadosawa, Takashi Kimura, T Umemura. Arteriovenous malformation of the cervical spinal cord in a dog. JOURNAL OF COMPARATIVE PATHOLOGY, 121(1), 71-76, 1999. doi: 10.1053/jcpa.1998.0294
5. K Asano, M Murakami, D Endo, Takashi Kimura, T Fujinaga. Complementary DNA cloning, tissue distribution, and synthesis of canine brain natriuretic peptide. AMERICAN JOURNAL OF VETERINARY RESEARCH, 60(7), 860-864, 1999.
6. K Ochiai, K Ohashi, T Mukai, Takashi Kimura, T Umemura, C Itakura. Evidence of neoplastic nature and viral aetiology of so-called fowl glioma. VETERINARY RECORD, 145(3), 79-81, 1999.
7. D Mikami, JH Park, Takashi Kimura, K Ochiai, C Itakura. Hepatic lesions in young rabbits experimentally infected with rabbit haemorrhagic disease virus. RESEARCH IN VETERINARY SCIENCE, 66(3), 237-242, 1999. doi: 10.1053/rvsc.1998.0266
8. T Hirai, M Mizutani, Takashi Kimura, K Ochiai, T Umemura, C Itakura. Neurotoxic effects of 2,5-hexanedione on normal and neurofilament-deficient quail. TOXICOLOGIC PATHOLOGY, 27(3), 348-353, 1999. doi: 10.1177/019262339902700311
9. T Mizutani, M Ogino, Y Nishino, Takashi Kimura, H Inagaki, D Hayasaka, H Kariwa, Takashima, I. Single-step reverse transcriptase polymerase chain reaction for detection of Borna disease virus RNA in vitro and in vivo. JAPANESE JOURNAL OF VETERINARY RESEARCH, 46(4), 165-169, 1999. doi: 10.14943/jjvr.46.4.165

1998年

1. T Mizutani, M Ogino, Y Nishino, Takashi Kimura, H Kariwa, K Tsujimura, H Inagaki, Takashima, I. A single-tube RT-PCR method for the detection of Borna disease viral genomic RNA. JAPANESE JOURNAL OF VETERINARY RESEARCH, 46(2-3), 73-81, 1998.
2. KO Cho, Takashi Kimura, K Ochiai, C Itakura. Gizzard adenocarcinoma in an aged Humboldt penguin (Spheniscus humboldti). AVIAN PATHOLOGY, 27(1), 100-102, 1998. doi: 10.1080/03079459808419281
3. Y Okada, K Ochiai, K Osaki, Takashi Kimura, C Itakura. Bronchiolar-alveolar carcinoma in a cow. JOURNAL OF COMPARATIVE PATHOLOGY, 118(1), 69-74, 1998.

1997年

1. KO Cho, D Endoh, Takashi Kimura, K Ochiai, C Itakura. Significance of Marek's disease virus serotype 1-specific phosphorylated proteins in Marek's disease skin lesions. AVIAN PATHOLOGY, 26(4), 707-720, 1997. doi: 10.1080/03079459708419247
2. T Hirai, M Mubarak, Takashi Kimura, K Ochiai, C Itakura. Apocrine gland tumor of the eyelid in a dog. VETERINARY PATHOLOGY, 34(3), 232-234, 1997.
3. 伊藤謙一, 川嶋和晴, 大庭芳和, 播谷亮, 木村享史, 板倉智敏. 静岡県における兎出血病の発生．. 日本獣医師会雑誌, 50(9), 523-526, 1997. doi: 10.12935/jvma1951.50.523

1996年

1. S Tanaka, IS Braga, Takashi Kimura, K Ochiai, C Itakura, M Mizutani. Inherited muscular disorder in mutant Japanese quail (Coturnix coturnix japonica): An immunohistochemical study. JOURNAL OF COMPARATIVE PATHOLOGY, 115(2), 139-150, 1996.
2. KO Cho, M Mubarak, Takashi Kimura, K Ochiai, C Itakura. Sequential skin lesions in chickens experimentally infected with Marek's disease virus. AVIAN PATHOLOGY, 25(2), 325-343, 1996. doi: 10.1080/03079459608419144
3. S Tanaka, IS Braga, Takashi Kimura, K Ochiai, C Itakura, M Mizutani. Inherited muscular disorder in mutant Japanese quail (Coturnix coturnix japonica): An ultrastructural study. JOURNAL OF COMPARATIVE PATHOLOGY, 114(3), 325-337, 1996. doi: 10.1016/S0021-9975(96)80054-5

1995年

1. IS BRAGA, S TANAKA, Takashi Kimura, C ITAKURA, M MIZUTANI. INHERITED MUSCULAR DISORDER IN MUTANT JAPANESE-QUAIL (COTURNIX-COTURNIX-JAPONICA) - RELATIONSHIP BETWEEN THE DEVELOPMENT OF MUSCLE LESIONS AND AGE. JOURNAL OF COMPARATIVE PATHOLOGY, 113(2), 131-143, 1995.

1994年

1. Takashi Kimura, J KIMURAKURODA, K NAGASHIMA, K YASUI. ANALYSIS OF VIRUS-CELL BINDING CHARACTERISTICS ON THE DETERMINATION OF JAPANESE ENCEPHALITIS-VIRUS SUSCEPTIBILITY. ARCHIVES OF VIROLOGY, 139(3-4), 239-251, 1994.

1990年

1. 斎藤巨志, 中川勇三, 石原高文, 木村享史, 長嶋和郎. キスカル酸レセプター刺激によるイノシトールリン脂質代謝応答の加齢ラット海馬での増大．. 神経化学, 29, 472-473, 1990.

2026年

1. Ryo Kanomata, Tamami Suzuki, Suzune Tanaka, Keika Kishimoto, Takuma Goto, Aprilia Maharani, Katriya Chankow, Takashi Kimura, Jumpei Yamazaki, Keisuke Aoshima. DNA methylation profiling and growth inhibitory effects of decitabine in canine hemangiosarcoma cell lines. Research Square, 2026. doi: 10.21203/rs.3.rs-10623493/v1
2. Tamami Suzuki, Suzune Tanaka, Keika Kishimoto, Takuma Goto, Jumpei Yamazaki, Takashi Kimura, Keisuke Aoshima. Fluvastatin Plus Dipyridamole Suppresses Canine Hemangiosarcoma Growth in Patient-Derived Xenograft Models Through Lactate Dehydrogenase-Associated Cholesterol/Lipid Metabolism.. Veterinary and comparative oncology, 2026. doi: 10.1111/vco.70097
3. Thi Ngoc Thuy Duong, Michihito Sasaki, Yasuko Orba, Keisuke Aoshima, Osamu Ichii, Keisuke Maezono, Passawat Thammahakin, Haruto Eguchi, Shintaro Kobayashi, Hiroaki Kariwa. Maintenance of Hokkaido virus, a genotype of Orthohantavirus puumalaense , in the rodent host Myodes rufocanus bedfordiae under natural conditions. Journal of Virology, 2026. doi: 10.1128/jvi.00321-26
4. Yuki Kawakami, Kensuke Nakamura, Hironobu Yasui, Keisuke Aoshima, Noboru Sasaki, Nozomu Yokoyama, Mitsuyoshi Takiguchi. Influence of airway pressure and fibrosis on lung surface shear wave elastography.. Journal of medical ultrasonics (2001), 2026. doi: 10.1007/s10396-026-01649-1
5. Tamami Suzuki, Kazuki Heishima, Jumpei Yamazaki, Masaya Yamazaki, Ryohei Kinoshita, Sangho Kim, Kenji Hosoya, Yuko Okamatsu-Ogura, Michihito Sasaki, Peng Xu, Takashi Kimura, Qin Yan, Keisuke Aoshima. Lysine lactylation regulates ATF4-mediated stress responses under glucose starvation in canine hemangiosarcoma. Frontiers in Veterinary Science, 13, 2026. doi: 10.3389/fvets.2026.1734339

2025年

1. Ai Koshikawa, Shingo Miki, Sangho Kim, Takashi Kimura, Keisuke Aoshima. Calcinosis circumscripta of the extremities and the tongue with multifocal arterial calcification secondary to chronic kidney disease in a cat.. The Journal of veterinary medical science, 2025. doi: 10.1292/jvms.25-0042
2. Takafumi Sunaga, Shingo Miki, Fuka Takahashi, Keisuke Aoshima, Sangho Kim, Masahiro Okumura. Progressive myelomalacia with spinal cord disorders along with severe intradural hemorrhage in a cat.. The Journal of veterinary medical science, 2025. doi: 10.1292/jvms.23-0493
3. Keita Kakisaka, Nozomu Yokoyama, Fuka Takahashi, Keisuke Aoshima, Mitsuyoshi Takiguchi. Ultrasonographic features and blood biochemistry findings of cholangiocarcinoma in a captive polar bear (Ursus maritimus). Veterinary Record Case Reports, 2025. doi: 10.1002/vrc2.70127

2024年

1. Tamami Suzuki, Michael James Henshaw, Teruki Yanagi, Keisuke Aoshima. Current understanding of comparative pathology and prospective research approaches for canine hemangiosarcoma.. Research in veterinary science, 167, 105120, 2024. doi: 10.1016/j.rvsc.2023.105120

2023年

1. N Nagata, Keisuke Aoshima, K Nakamura, M Takiguchi. Adrenocortical hypoperfusion detected by contrast-enhanced ultrasound in a dog with trilostane-induced hypoadrenocorticism.. The Journal of small animal practice, 64(11), 722-726, 2023. doi: 10.1111/jsap.13643
2. Yu Asari, Jumpei Yamazaki, Oo Thandar, Tamami Suzuki, Keisuke Aoshima, Kyosuke Takeuchi, Ryohei Kinoshita, Sangho Kim, Kenji Hosoya, Teita Ishizaki, Yumiko Kagawa, Jaroslav Jelinek, Shoko Yokoyama, Noboru Sasaki, Hiroshi Ohta, Kensuke Nakamura, Mitsuyoshi Takiguchi. Diverse genome-wide DNA methylation alterations in canine hepatocellular tumours.. Veterinary medicine and science, 2023. doi: 10.1002/vms3.1204
3. Mei Sugawara-Suda, Keitaro Morishita, Osamu Ichii, Takashi Namba, Keisuke Aoshima, Yumiko Kagawa, Sangho Kim, Kenji Hosoya, Nozomu Yokoyama, Noboru Sasaki, Kensuke Nakamura, Jumpei Yamazaki, Mitsuyoshi Takiguchi. Transcriptome and proteome analysis of dogs with precursor targeted immune-mediated anemia treated with splenectomy.. PloS one, 18(5), e0285415, 2023. doi: 10.1371/journal.pone.0285415

2022年

1. Hiroya Konno, Nozomu Yokoyama, Yu Tamura, Keisuke Aoshima, Ryo Nakao, Mitsuyoshi Takiguchi, Ken Katakura. An experimental challenge model for Leishmania donovani in beagle dogs, showing a similar pattern of parasite burden in the peripheral blood and liver.. Parasitology research, 121(12), 3569-3579, 2022. doi: 10.1007/s00436-022-07681-7
2. Kevin Christian M. Gulay, Keisuke Aoshima, Sangho Kim, Ryusei Kitaguchi, Atsushi Kobayashi, Takashi Kimura. The expression of histone lysine demethylase 2B in canine hemangiosarcoma is associated with disease progression. Veterinary and Comparative Oncology, 20(2), 529-534, 2022. doi: 10.1111/vco.12796
3. Noboru Sasaki, Yoshinori Ikenaka, Keisuke Aoshima, Teiichiro Aoyagi, Nobuki Kudo, Kensuke Nakamura, Mitsuyoshi Takiguchi. Safety Assessment of Ultrasound-Assisted Intravesical Chemotherapy in Normal Dogs: A Pilot Study. Frontiers in Pharmacology, 13, 837754, 2022. doi: 10.3389/fphar.2022.837754
4. Kevin Christian M. Gulay, Keisuke Aoshima, Naoya Maekawa, Tamami Suzuki, Satoru Konnai, Atsushi Kobayashi, Takashi Kimura, *Corresponding author. Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages. Scientific Reports, 12(1), 2124, 2022. doi: 10.1038/s41598-022-06203-w
5. Meiling Zhang, Zongzhi Z. Liu, Keisuke Aoshima, Wesley L. Cai, Hongyin Sun, Tianrui Xu, Yangyi Zhang, Yongyan An, Jocelyn F. Chen, Lok Hei Chan, Asako Aoshima, Sabine M. Lang, Zhenwei Tang, Xuanlin Che, Yao Li, Sara J. Rutter, Veerle Bossuyt, Xiang Chen, Jon S. Morrow, Lajos Pusztai, David L. Rimm, Mingzhu Yin, Qin Yan. CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression. Science Translational Medicine, 2022. doi: 10.1126/scitranslmed.abf5473

2019年

1. Gale M, Li Y, Cao J, Liu ZZ, Holmbeck MA, Zhang M, Lang SM, Wu L, Do Carmo M, Gupta S, Keisuke Aoshima, DiGiovanna MP, Stern DF, Rimm DL, Shadel GS, Chen X, Yan Q. Acquired resistance to HER2-targeted therapies creates vulnerability to ATP synthase inhibition.. Cancer research, 2019. doi: 10.1158/0008-5472.can-18-3985

2018年

1. H.M. Suranji Wijekoon, Sangho Kim, Eugene C. Bwalya, Jing Fang, Keisuke Aoshima, Kenji Hosoya, Masahiro Okumura. Anti-arthritic effect of pentosan polysulfate in rats with collagen-induced arthritis. Research in Veterinary Science, 122, 179-185, 2018. doi: 10.1016/j.rvsc.2018.11.028
2. Raghda M. F. Abbas, Hassan T. Tag-El-Din-Hassan, Tussapon Boonyarattanasoonthorn, Keisuke Aoshima, Masami Morimatsu, Takashi Agui. Immune cellular responses to sendai virus infection in D2.B6-Sen1Sen2Sen3 congenic mice, of which three quantitative trait loci responsible for the resistance to infection were introgressed from C57BL/6 mouse into DBA/2 mouse. Japanese Journal of Veterinary Research, 66(2), 93-103, 2018. doi: 10.14943/jjvr.66.2.93

2017年

1. Yusuke Izumi, Keisuke Aoshima, Yuki Hoshino, Satoshi Takagi. Effects of combretastatin A-4 phosphate on canine normal and tumor tissue derived endothelial cells. RESEARCH IN VETERINARY SCIENCE, 112, 222-228, 2017. doi: 10.1016/j.rvsc.2017.05.017

2015年

1. Yuki Okada, Keisuke Aoshima. KM mutant highlights enhancers in minor ZGA. CELL CYCLE, 14(16), 2541-2542, 2015. doi: 10.1080/15384101.2015.1060774
2. Keisuke Aoshima, Erina Inoue, Hirofumi Sawa, Yuki Okada. Paternal H3K4 methylation is required for minor zygotic gene activation and early mouse embryonic development. EMBO REPORTS, 16(7), 803-812, 2015. doi: 10.15252/embr.201439700

2014年

1. Sawang Kesdangsakonwut, Yuji Sunden, Keisuke Aoshima, Yoshimi Iwaki, Masahiro Okumura, Hirofumi Sawa, Takashi Umemura. Survival of rabid rabbits after intrathecal immunization. NEUROPATHOLOGY, 34(3), 277-283, 2014. doi: 10.1111/neup.12094
2. Makino Y, Inoue E, Hada M, Keisuke Aoshima, Kitano S, Miyachi H, Okada Y. Generation of a dual-color reporter mouse line to monitor spermatogenesis in vivo.. Frontiers in cell and developmental biology, 2, 30, 2014. doi: 10.3389/fcell.2014.00030

2013年

1. Keisuke Aoshima, Ai Baba, Yoshinori Makino, Yuki Okada. Establishment of Alternative Culture Method for Spermatogonial Stem Cells Using Knockout Serum Replacement. PLOS ONE, 8(10), e77715, 2013. doi: 10.1371/journal.pone.0077715
2. Keisuke Aoshima. [Chromatin dynamics in mouse pronuclear zygotes].. Seikagaku. The Journal of Japanese Biochemical Society, 85(4), 278-283, 2013.

2011年

1. Keisuke Aoshima, Yuji Sunden, Sachiyo Ishida, Kenji Ochiai, Takashi Umemura. Possible Origin of CSF Antibodies Induced by Intrathecal Immunization and Prophylactic Effects against Intracerebral Rabies Virus Infection. JOURNAL OF VETERINARY MEDICAL SCIENCE, 73(10), 1303-1308, 2011. doi: 10.1292/jvms.11-0183