2016

Original articles

 

1 ) Ohira, K., Nakahara, A., Konnai, S., Okagawa, T., Nishimori, A., Maekawa, N., Ikebuchi, R., Murata, S. and Ohashi, K. 2016. Bovine leukemia virus reduces anti-viral cytokine activities and NK cytotoxicity by inducing TGF-β secretion from regulatory T cells. Immun. Inflamm. Dis., in press.

 

2 ) Ochirkhuu, N., Konnai, S., Odbileg, R., Nishimori, A., Okagawa, T., Murata, S., Ohashi, K. 2016. Detection of bovine leukemia virus and identification of its genotype in Mongolian cattle. Arch. Virol., in press.

 

3 ) Toyomane, K., Konnai, S., Niwa, A., Githaka, W. N., Isezaki, M., Yamada, S., Ito, T., Takano, A., Ando, S., Kawabata, H., Murata, S. and Ohashi, K. 2016. Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze. Ticks Tick Borne Dis., 7: 119-125. (doi: 10.1016/j.ttbdis.2015.09.006)

 

2015

Original articles

 

1 ) Gomes, H., Moraes, J., Githaka, N., Martins, R., Isezaki, M., Vaz Ida, S. Jr., Logullo, C., Konnai, S., and Ohashi, K. 2015. Vaccination with cyclin-dependent kinase tick antigen confers protection against Ixodes infestation. Vet. Parasitol., 211: 266-273. (doi: 10.1016/j.vetpar.2015.05.022)

 

2 ) Nakata, H., Nakayama, S. M., Ikenaka, Y., Mizukawa, H., Ishii, C., Yohannes, Y. B., Konnai, S., Darwish, W. S. and Ishizuka, M. 2015. Metal extent in blood of livestock from Dandora dumping site, Kenya: Source identification of Pb exposure by stable isotope analysis. Environ. Pollut., 205: 8-15. (doi: 10.1016/j.envpol.2015.05.003)

 

3 ) Ochirkhuu, N., Konnai, S., Mingala, C., Okagawa, T., Villanueva, M., Pilapil, F., Murata, S. and Ohashi, K. 2015. Molecular epidemiological survey and genetic analysis of vector-borne infections of cattle in Luzon Island, the Philippines. Vet. Parasitol., 212: 161-167. (doi: 10.1016/j.vetpar.2015.05.019)

 

4 ) Mekata, H., Sekiguchi, S., Konnai, S., Kirino, Y., Horii, Y. and Norimine, J. 2015. Horizontal transmission and phylogenetic analysis of bovine leukemia virus in two districts of Miyazaki, Japan. J. Vet. Med. Sci., 77: 1115-1120. (doi: 10.1292/jvms.14-0624)

 

5 ) Gondaira, S., Higuchi, H., Iwano, H., Nakajima, K., Kawai, K., Hashiguchi, S., Konnai, S., Nagahata, H. 2015. Cytokine mRNA profiling and the proliferative response of bovine peripheral blood mononuclear cells to Mycoplasma bovis. Vet. Immunol. Immunopathol. 165: 45-53. (doi: 10.1016/j.vetimm.2015.03.002)

 

6 ) Mekata, H., Murata, S., Mingala, C. N., Ohashi, K. and Konnai, S. 2015. Expression of regulatory dendritic cell-related cytokines in cattle experimentally infected with Trypanosoma evansi. J. Vet. Med. Sci., 77: 1017-1019. (doi: 10.1292/jvms.15-0066)

 

7 ) Parizi, L., Sabadin, G., Alzugaray, M., Seixas, A., Logullo, C., Konnai, S., Ohashi, K., Masuda, A. and da Silva Vaz, I. Jr. 2015. Rhipicephalus microplus and Ixodes ovatus cystatins in tick blood digestion and evasion of host immune response. Parasit. Vectors, 8: 122. (doi:10.1186/s13071-015-0743-3)

 

8 ) Murase, Y., Konnai, S., Yamada, S., Githaka, W. N., Isezaki, M., Ito, T., Takano, A., Ando, S., Kawabata, H., Murata, S. and Ohashi, K. 2015. An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes. Insect Biochem. Mol. Biol., 60: 59-67. (doi: 10.1016/j.ibmb.2015.01.010)

 

9 ) da Silva, R. M., Noce, B. D., Waltero, C. F., Costa, E. P., de Abreu, L. A., Githaka, N. W., Moraes, J., Gomes, H. F., Konnai, S., Vaz Ida ,S. Jr., Ohashi, K. and Logullo, C. 2015. Non-classical gluconeogenesis-dependent glucose metabolism in Rhipicephalus microplus embryonic cell line BME26. Int. J. Mol. Sci., 16: 1821-1839. (doi: doi: 10.3390/ijms16011821)

 

10) Suzuki, S., Konnai, S., Okagawa, T., Ikebuchi, R., Nishimori, A., Kohara, J., Mingala, C. N., Murata, S. and Ohashi, K. 2015. Increased expression of the regulatory T cell-associated marker CTLA-4 during in bovine leukemia virus infection. Vet. Immunol. Immunopathol., 163: 115-124. (doi: 10.1016/j.vetimm.2014.10.006)

 

11) Kakinuma, S., Izawa, T., Matsuda, K., Konnai, S., Maeda, Y. and Ohtsuka, H. 2015. Cellular immune response to interferon-tau in peripheral blood mononuclear cells of Japanese black cattle with bovine leukemia virus infection. Acta Vet. (Beograd), 65: 287–296. (doi: 10.1515/acve-2015-0024)

 

12) Okagawa, T., Konnai, S., Nishimori, A., Ikebuchi, R., Mizorogi, S., Nagata, R., Kawaji, S., Tanaka, S., Kagawa, Y., Murata, S., Mori, Y. and Ohashi, K. 2015. Bovine immunoinhibitory receptors contribute to the suppression of Mycobacterium avium subsp. paratuberculosis-specific T-cell responses. Infect. Immun., 84: 77-89. (10.1128/IAI.01014-15)

 

13 ) Duran, P., Padiernos, R., Abella, E., Konnai, S. and Mingala, C. 2015. Molecular Characterization of TIM-3 and Gal-9 Genes in Swamp and Riverine Buffaloes. Int. J. Immunogenet., 42: 469-478. (doi: 10.1111/iji.12235)

 

14) Ochirkhuu, N., Konnai, S., Odbileg, R., Murata, S. and Ohashi, K. 2015. A preliminary survey of the seroprevalence of Mycobacterium avium subspecies paratuberculosis in Mongolian cattle. Jpn. J. Vet. Res., 63: 191-194. (doi: 10.14943/jjvr.63.4.191)

 

2014

Original articles

 

1 ) Ikebuchi, R., Konnai, S., Okagawa T., Yokoyama, K., Nakajima, C., Suzuki, Y., Murata, S. and Ohashi K. 2014. Influence of PD-L1 cross-linking on cell death in PD-L1-expressing cell lines and bovine lymphocytes. Immunology, 142: 551-561. (doi: 10.1111/imm.12243)

 

2 ) Hidano, A., Konnai, S., Yamada, S., Yoshimura, H., Githaka, N., Isezaki, M., Higuchi, H., Nagahata, H., Ito, T., Takano, A., Ando, S., Kawabata, H., Murata S. and Ohashi, K. 2014. Suppressive effects of neutrophil by Salp16-like salivary gland proteins from Ixodes persulcatus Schulze tick. Insect Mol. Biol., 23: 466-474. (doi: 10.1111/imb.12101)

 

3 ) Githaka, N., Konnai, S., Bishop, R., Odongo, D., Lekolool, I., Kariuki, E., Gakuya, F., Kamau, L., Isezaki, M., Murata, S. and Ohashi, K. 2014. Identification and sequence characterization of novel Theileria genotypes from the waterbuck (Kobus defassa) in a Theileria parva-endemic area in Kenya. Vet. Parasitol., 202: 180-193. (doi: 10.1016/j.vetpar.2014.02.056)

 

4 ) Maekawa, N., Konnai, S., Ikebuchi, R., Okagawa, T., Adachi, M., Takagi, S., Kagawa, Y., Nakajima, C., Suzuki, Y., Murata, S. and Ohashi, K. 2014. Expression of PD-L1 on canine tumor cells and enhancement of IFN-γ production from tumor infiltrating cells by PD-L1 blockade. PLoS One, 9: e98415. (doi: 10.1371/journal.pone.0098415)

 

5 ) Ikebuchi, R., Konnai, S., Okagawa, T., Nishimori, A., Nakahara, A., Murata, S. and Ohashi, K. 2014. Differences in cellular function and viral protein expression between IgM high and IgM low B cells in bovine leukemia virus-infected cattle. J. Gen. Virol., 95: 1832-1842. (doi: 10.1099/vir.0.065011-0)

 

6 ) Nishimori, A., Konnai, S., Ikebuchi, R., Okagawa, T., Nakajima, C., Suzuki, Y., Mingala, C., Murata, S. and Ohashi, K. 2014. Identification and characterization of bovine programmed death-ligand 2. Microbiol. Immunol., 58: 388-397. (doi: 10.1111/1348-0421.12160)

 

7 ) Matsuyama-Kato, A., Murata, S., Isezaki, M., Takasaki, S., Kano, R., Konnai, S. and Ohashi, K. 2014. Expression analysis of programmed death ligand 2 in tumors caused by the avian oncovirus Marek’s disease virus. Arch. Virol., 159: 2123-2136. (doi: 10.1007/s00705-014-2021-7)

 

8 ) Ali, A., Tirloni, L., Isezaki, M., Seixas, A., Konnai, S., Ohashi, K., da Silva, Vaz I. Jr. and Termignoni, C. 2014. Reprolysin metalloproteases from Ixodes persulcatus, Rhipicephalus sanguineus and Rhipicephalus microplus ticks. Exp. Appl. Acarol., 63: 559-578.(doi: 10.1007/s10493-014-9796-9)

 

9 ) Sato, K., Takano, A., Konnai, S., Nakao, M., Ito, T., Koyama, K., Kaneko, M., Ohnishi, M. and Kawabata H. 2014. Human Borrelia miyamotoi infections in Japan. Emerg. Infect. Dis., 20: 1391-1393. (doi: 10.3201/eid2008.131761)

 

10) Lee, K., Takano, A., Kaylor, K. R., Sashika, M., Shimozuru, M., Konnai, S., Kawabata, H. and Tsubota, T. 2014. A Relapsing fever group Borrelia sp. similar to Borrelia lonestari found among wild sika deer (Cervus nippon yesoensis) and Haemaphysalis spp. ticks in Hokkaido, Japan. Ticks Tick Borne Dis., 5: 841-847. (doi: 10.1016/j.ttbdis.2014.06.006)

 

11) Takano, A., Toyomane, K., Konnai, S., Ohashi, K., Nakao, M., Ito, T., Andoh, M., Maeda, K., Watarai, M., Sato, K. and Kawabata, H. 2014. Tick surveillance for relapsing fever spirochete Borrelia miyamotoi in Hokkaido, Japan. PLoS One, 9: e104532. (doi: 10.1371/journal.pone.0104532)

 

2013

Original articles

 

1 ) Ooshiro, M., Konnai, S., Katagiri, Y., Afuso, M., Arakaki, N., Tsuha, O., Murata, S. and Ohashi, K. 2013. Horizontal transmission of bovine leukemia virus from lymphocytotic cattle, and beneficial effects of insect vector control. Vet. Rec., 173: 527.

 

2 ) Gomes, H., Romeiro, N. C., Braz, G. R., de Oliveira, E. A., Rodrigues, C., da Fonseca, R. N., Githaka, N., Isezaki, M., Konnai, S., Ohashi, K., da Silva Vaz, I. Jr., Logullo, C. and Moraes, J. 2013. Identification and structural-functional analysis of cyclindependent kinases of the cattle tick Rhipicephalus (Boophilus) microplus. PLoS One, 8: e76128.

 

3 ) Parizi, L. F., Githaka, N. W., Acevedo, C., Benavides, U., Seixas, A., Logullo, C., Konnai, S., Ohashi, K., Masuda, A. and da Silva Vaz, I. Jr. 2013. Sequence characterization and immunogenicity of cystatins from the cattle tick Rhipicephalus (Boophilus) microplus. Ticks Tick Borne Dis., 4: 492-499.

 

4 ) Suzuki, S., Konnai, S., Okagawa, T., Ikebuchi, R., Shirai, T., Sunden, Y., Mingala, C. N., Murata, S. and Ohashi, K. 2013. Expression analysis of Foxp3 in T cells from bovine leukemia virus infected cattle. Microbiol. Immunol., 57: 600-604.

 

5 ) Ikebuchi, R., Konnai, S., Okagawa, T., Yokoyama, K., Nakajima, C., Suzuki, Y., Murata, S. and Ohashi, K. 2013. Blockade of bovine PD-1 increases T cell function and inhibits bovine leukemia virus expression in B cells in vitro. Vet. Res., 44: 59.

 

6 ) Githaka, N., Konnai, S., Skilton, R., Kariuki, E., Kanduma, E., Murata, S. and Ohashi, K. 2013. Genotypic variations in field isolates of Theileria species infecting giraffes (Giraffa camelopardalis tippelskirchi and Giraffa camelopardalis reticulata) in Kenya. Parasitol. Int., 62: 448-453.

 

7 ) Imamura, S., Nakamizo, M., Kawanishi, M., Nakajima, N., Yamamoto, K., Uchiyama, M., Hirano, F., Nagai, H., Kijima, M., Ikebuchi, R., Mekata, H., Murata, S., Konnai, S. and Ohashi, K. 2013. Bovine whole-blood culture as a tool for the measurement of endotoxin activities in Gram-negative bacterial vaccines.Vet. Immunol. Immunopathol., 153: 153-158.

 

8 ) Mekata, H., Konnai, S., Mingala, C. N., Abes, N. S., Gutierrez, C. A., Dargantes, A. P., Witola, W. H., Inoue, N., Onuma, M., Murata, S. and Ohashi, K. 2013. Isolation, cloning, and pathologic analysis of Trypanosoma evansi field isolates. Parasitol. Res., 112: 1513-1521.

 

9 ) Murata, S., Hashiguchi, T., Hayashi, Y., Yamamoto, Y., Matsuyama-Kato, A., Takasaki, S., Isezaki, M., Onuma, M., Konnai, S. and Ohashi, K. 2013. Characterization of Meq proteins from field isolates of Marek’s disease virus in Japan. Infect. Genet. Evol.,16: 137-143.

 

10) de Abreu, L. A., Calixto, C., Waltero, C. F., Della Noce, B. P., Githaka, N. W., Seixas, A., Parizi, L. F., Konnai, S., Vaz Ita, S., Ohashi, K. and Logullo, C. 2013. The conserved role of the AKT/GSK3 axis in cell survival and glycogen metabolism in Rhipicephalus (Boophilus) microplus embryo tick cell line BME26. Biochim. Biophys. Acta, 1830: 2574-2582.

 

11) Taylor, K. R., Takano, A., Konnai, S., Shimozuru, M., Kawabata, H. and Tsubota, T. 2013. Differential tick burdens may explain differential Borrelia afzelii and Borrelia garinii infection rates among four, wild, rodent species in Hokkaido, Japan. J. Vet. Med. Sci., 75: 785-790.

 

12) Taylor, K. R., Takano, A., Konnai, S., Shimozuru, M., Kawabata, H. and Tsubota, T. 2013. Borrelia miyamotoi infections among wild rodents show age and month independence and correlation with Ixodes persulcatus larval attachment in Hokkaido, Japan. Vector Borne Zoonotic Dis., 13: 92-97.

 

13) Konnai, S., Suzuki, S., Shirai, T., Ikebuchi, R., Okagawa, T., Sunden, Y., Mingala, C. N., Onuma, M., Murata, S. and Ohashi, K. 2013. Enhanced expression of LAG-3 on lymphocyte subpopulations from persistently lymphocytotic cattle infected with bovine leukemia virus. Comp. Immunol. Microbiol. Infect. Dis., 36: 63-69.

 

Publications other than original articles

 

1 ) Konnai, S., Murata, S. and Ohashi, K. 2013. Control strategies of bovine leukemia. Dairyman, 63: 42-43. (in Japanese).

 

2 ) Nishimori, A., Konnai, S., Ikebuchi, R., Okagawa, T., Murata, S. and Ohashi, K.2013. Immune functions of PD-L1 and PD-L2 and its clinical applications. The Japanese Society for Animal Vaccine and Biomedical Research News Letter, 8: 18-19. (in Japanese).

 

3) Konnai, S. 2013. Recent findings in bovine infection immunity. Journal of the Japan Veterinary Medical Association, 66: 171-179. (in Japanese).

 

4) Asakawa, M., Nakade, T., Murata, S., Ohashi, K., Osa, Y. and Taniyama, H. 2013. Recent viral disease of Japanese Anatid with a fatal case of Marek’s disease in an endangered species, white-fronted goose (Anser albifrons). In: Ducks: Habitat, Behavior, and Diseases, pp. 37-47, Hambrick, J. and Gammon, L. T. eds., Nova Science Publishers, New York.

 

2012

Original articles

 

1 ) Githaka, N., Konnai, S., Kariuki, E., Kanduma, E., Murata, S. and Ohashi, K. 2012. Molecular detection of new Babesia and Theileria species/variants in wild felids from Kenya. Acta Tropica124: 71-78.

2 ) Suzuki, S., Konnai, S., Okagawa, T., Githaka, N., Kariuki, E., Gakuya, F., Kanduma, E., Shirai, T., Ikebuchi, R., Ikenaka, Y., Ishizuka, M., Murata, S. and Ohashi, K. 2012. Molecular cloning and characterization of Th1 and Th2 cytokines of African buffalo (Syncerus caffer). Int. J. Immunogenet.39: 170-182.

3 ) Takano, A., Sugimori, C., Fujita, H., Kadosaka, T., Taylor, K. R., Tsubota, T., Konnai, S., Tajima, T., Sato, K., Watanabe, H., Ohnishi, M. and Kawabata, H. 2012. A novel relapsing fever Borrelia sp. infects the salivary glands of the molted hard tick, Amblyomma geoemydae. Ticks Tick Borne Dis.3: 259-261.

4 ) Matsuyama-Kato, A., Murata, S., Isezaki, M., Kano, R., Takasaki, S., Ichii, O., Konnai, S. and Ohashi, K. 2012. Molecular characterization of immunoinhibitory factors PD-1/PD-L1 in chickens infected with Marek’s disease virus. Virol. J.9: 94.

5 ) Okagawa, T., Konnai, S., Mekata, H., Githaka, N., Suzuki, S., Kariuki, E., Gakuya, F., Kanduma, E., Shirai, T., Ikebuchi, R., Ikenaka, Y., Ishizuka, M., Murata, S. and Ohashi, K. 2012. Transcriptional profiling of inflammatory cytokine genes in Theileria parva-infected African buffalo (Syncerus caffer). Vet. Immunol. Immunopathol.148: 373-279

6 ) Kohara, J., Nishikura, Y., Konnai, S., Tajima, M. and Onuma, M. 2012. Effects of interferon tau on cattle persistently infected with bovine viral diarrhea virus. Jpn. J. Vet. Res.60: 63-70.

7 ) Okagawa, T., Konnai, S., Ikebuchi, R., Suzuki, S., Shirai, T., Sunden, Y., Onuma M., Murata, S. and Ohashi, K. 2012. Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection. Vet. Res.43: 45.

8 ) Konnai, S., Yamada, S., Imamura, S., Nishikado, H., Githaka, W. N., Ito, T., Takano, A., Kawabata, H., Murata, S. and Ohashi, K. 2012. Identification of TROSPA homologue inIxodes persulcatus, Schulze, the specific vector for human Lyme borreliosis in Japan. Ticks Tick Borne Dis.3: 75-77.

9 ) Ikenaka, Y., Nakayama, S. M., Muroya, T., Yabe, J., Konnai, S., Darwish, W. S., Muzandu, K., Choongo, K., Mainda, G., Teraoka, H., Umemura, T. and Ishizuka, M. 2012. Effects of environmental lead contamination on cattle in a lead/zinc mining area: Changes in cattle immune systems on exposure to lead in vivo and in vitro. EnvironToxicol. Chem.31: 2300-2305.

10) Mekata, H., Konnai, S., Mingala, C. N., Abes, N. S., Gutierrez, A., Dargantes, A. P., Witola, W. H., Inoue, N., Onuma, M., Murata, S. and Ohash, K. 2012. Kinetics of regulatory dendritic cells in inflammatory responses during Trypanosoma evansi infection. Parasite Immunol.34: 318-329.

 

11 ) Murata, S., Hayashi, Y., Kato, A., Isezaki, M., Takasaki, S., Onuma, M., Osa, Y., Asakawa, M., Konnai, S., Ohashi, K. 2012. Surveillance of Marek’s disease virus in migratory and sedentary birds in Hokkaido, Japan. Vet. J., 192: 538-540.

 

12) Parizi, L. F., Githaka, N. W., Logullo, C., Konnai, S., Masuda, A., Ohashi, K. and da Silva, Vaz, Jr. I. 2012. The quest for a universal vaccine against ticks: Cross-immunity insights. Vet. J.194: 158-165.

 

Publications other than original articles

 

1 ) Ohashi, K., Murata, S. and Konnai, S. 2012. Basic immunology of infectious diseases (What’s immunology). Journal of Clinical Veterinary Medicine8: 60-62. (in Japanese).

2 ) Murata, S., Konnai, S. and Ohashi, K. 2012. Basic immunology of infectious diseases (Humoral immunity). Journal of Clinical Veterinary Medicine9: 60-62. (in Japanese). 

3 ) Konnai, S., Murata, S. and Ohashi, K. 2012. Basic immunology of infectious diseases (Cellular immunity). Journal of Clinical Veterinary Medicine10: 42-44. (in Japanese). 

4 ) Ohashi, K., Murata, S. and Konnai, S. 2012. Basic immunology of infectious diseases (Recent topics in veterinary immunology). Journal of Clinical Veterinary Medicine11: 50-52. (in Japanese).

5 ) Konnai, S. 2012. Control strategies of bovine leukemia. Journal of Clinical Veterinary Medicine6: 44-49. (in Japanese). 

6 ) Konnai, S., Murata, S. and Ohashi, K. 2012. Increasing bovine leukemia and its control measures in Hokkaido. J. Hokkaido Vet. Med. Assoc.56: 1-7. (in Japanese).

7 ) Konnai, S. 2012. Control measures of bovine leukemia virus infection in large dairy hard. Dairy journal, 4: 15-18. (in Japanese).

 

2011

Original articles

 

1 ) Ikebuchi, R., Konnai, S., Shirai, T., Sunden, Y., Murata, S., Onuma, M., Ohashi, K. 2011. Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade. Vet. Res. 42: 103. 

2 ) Murase, Y., Konnai, S., Hidano, A., Githaka, W.N., Ito, T., Takano, A., Kawabata, H., Ato, M., Tajima, T., Tajima, M., Onuma, M., Murata, S., Ohashi, K. 2011. Molecular detection of Anaplasma phagocytophilum in cattle and Ixodes persulcatus ticks. Vet. Microbiol49: 504-507. 

3 ) Konnai, S., Nishikado, H., Yamada, S., Imamura, S., Ito, T., Onuma, M., Murata, S., Ohashi, K. 2011. Molecular identification and expression analysis of lipocalins from blood feeding taiga tick, Ixodes persulcatus Schulze. Exp. Parasitol. 127: 467-474. 

4 ) Shirai, T., Konnai, S., Ikebuchi, R., Okagawa, T., Suzuki, S., Sunden, Y., Onuma, M., Murata, S., Ohashi, K. 2011. Molecular cloning of bovine lymphocyte activation gene-3 and its expression characteristics in bovine leukemia virus-infected cattle. Vet. Immunol. Immunopathol. 144: 462-467.

5 ) Takano, A., Fujita, H., Kadosaka, T., Konnai, S., Tajima, T., Watanabe, H., Ohnishi, M., Kawabata, H. 2011. Characterization of reptile-associated Borrelia sp. in the vector tick, Amblyomma geoemydae, and its association with Lyme disease and relapsing fever Borrelia spp. Environ. Microbiol. Rep.3: 632-637. 

6 ) Takano, A., Nakao, M., Masuzawa, T., Takada, N., Yano, Y., Ishiguro, F., Fujita, H., Ito, T., Ma, X., Oikawa, Y., Kawamori, F., Kumagai, K., Mikami, T., Hanaoka, N., Ando, S., Honda, N., Taylor, K., Tsubota, T., Konnai, S., Watanabe, H., Ohnishi, M., Kawabata, H. 2011. Multi-locus sequence typing implicates rodents as the main reservoir host of human pathogenicBorrelia garinii in Japan. J. Clin. Microbiol., 49: 2035-2039. 

7 ) Mingala, C.N., Konnai, S., Ikebuchi, R., Onuma, M., Ohashi, K. 2011. Characterization of CTLA-4, PD-1 and PDL-1 of swamp and riverine type water buffaloes. Comp. Immunol. Microbiol. Infect. Dis.34: 55-63. 

8 ) Murata, S., Okada, T., Kano, R., Hayashi, Y., Hashiguchi, T., Onuma, M., Konnai, S., Ohashi, K. 2011. Analysis of transcriptional activities of the Meq proteins present in highly virulent Marek’s disease virus strains, RB1B and Md5. Virus Genes, 43: 66-71. 

9 ) Parizi, L.F., Utiumi, K.U., Imamura, S., Onuma, M., Ohashi, K., Masuda, A., da Silva Vaz I. Jr. 2011. Cross immunity with Haemaphysalis longicornis glutathione S-transferase reduces an experimental Rhipicephalus (Boophilus) microplus infestation. Exp. Parasitol.,127: 113-118. 

 

Publications other than original articles

 

1 ) Konnai, S., 2011. Future prospective in vaccine development against bovine leukemia virus. The Japanese Journal of Animal Hygiene37: 81-84. (in Japanese) 

2 ) Konnai, S., 2011. Current topics and problems in control for bovine leukemia. Journal of Clinical Veterinary Medicine, 29: 14-18. (in Japanese) 

3 ) Konnai, S., Yasutomi, I., Tajima, M., Murata, S. and Ohashi, K. 2011. Control measures of bovine leukemia (part 1: reasons for increasing bovine leukemia). Dairy Japan9: 37-39. (in Japanese) 

4 ) Konnai, S., Yasutomi, I., Tajima, M., Murata, S. and Ohashi, K. 2011. Control measures of bovine leukemia (part 2: preventive measures). Dairy Japan, 10: 34-36. (in Japanese) 

5 ) Konnai, S., Yasutomi, I., Tajima, M., Murata, S. and Ohashi, K. 2011. Control measures of bovine leukemia (part 3: harmful rumor). Dairy Japan11: 57-59. (in Japanese) 

6 ) Konnai, S., Yasutomi, I., Tajima, M., Murata, S. and Ohashi, K. 2011. Control measures of bovine leukemia (part 4: practical approach in clinical field). Dairy Japan12: 62-64. (in Japanese) 

7) Konnai, S., Tajima, M., Murata, S. and Ohashi, K. 2011. Current status and control measures of bovine leukemia in Japan. Japanese Journal of Clinical Bovine Parasitology, 2: 2-3. (in Japanese) 

8 ) Konnai, S., Yasutomi, I., Tajima, M., Murata, S. and Ohashi, K. 2011. Overview of bovine leukemia, Holstein magazine505: 4-7. (in Japanese) 

9 ) Konnai, S., Yasutomi, I., Tajima, M., Murata, S. and Ohashi, K. 2011. Control measures of bovine leukemia by BLV, Dairyman61: 30-31.  (in Japanese)

10) Konnai, S., Tajima, M., Murata, S. and Ohashi, K. 2011. Control strategies of bovine leukemia, Hokkaido shakunagekai kaihou50: 10-12. (in Japanese) 

 

2010

Original articles

 

1 ) Ikebuchi, R., Konnai, S., Sunden, Y., Onuma M. and Ohashi K. 2010. Molecular cloning and expression analysis of bovine programmed death-1Microbiol. Immunol., 54: 291-298. (doi:10.1111/j.1348-0421.2010.00208.x)

2 ) Mori, A., Konnai, S., Yamada, S., Hidano, A., Murase, Y., Ito, T., Takano, A., Kawabata, H., Onuma, M. and Ohashi, K. 2010. Two novel Salp15-like immunosuppressant genes from salivary glands of Ixodes persulcatus Schulze tickInsect Mol. Biol.19: 359-365. (do:10.1111/j.1365-2583.2010.00994.x)
 

 

Publications other than original articles

 

1 ) Ohashi K., Murata S., Okada T. and Konnai S. 2010. The detection and characterization of the meq variants of Marek's diseases virusAnimal Viruses,16: 117-132. 

2 ) Konnai, S., Tajima, M., Onuma, M. and Ohashi, K. 2010. Current topics and control on Bovine leukemia virus infectionJ. Livestock Med.57: 201-207. (in Japanese) 

3 ) Konnai, S., Tajima, M., Onuma, M., Murata, S. and Ohashi, K. 2010. Current status and control measures of increasing bovine leukemia ‘for voices from clinical fieldJapanese Journal of Large Animal Clinics, 1: 110-114. (in Japanese). 

4 ) Konnai, S., 2010. Control of tick-borne diseases by anti-tick vaccineThe Japanese Journal of Animal Hygiene, 36: 73-75. (in Japanese). 

 

2009

Original articles

 

1 ) Konnai, S., Nakajima, C., Imamura, S., Yamada, S., Nishikado, H., Kodama, M., Onuma, M., and Ohashi, K. 2009. Suppression of cell proliferation and cytokine expression by HL-p36, a tick salivary gland-derived protein of Haemaphysalis longicornis.Immunology126: 209-219.

2 ) Yamada, S., Konnai, S., Imamura, S., Simuunza, M., Chembensofu, M., Chota, A., Nambota, A., Onuma, M., and Ohashi, K. 2009. Quantitative Analysis of Cytokine mRNA Expression and Protozoan DNA Load in Theileria parva-Infected Cattle. J. Vet. Med. Sci., 71: 49-54. 

3 ) Kano, R., Konnai, S., Onuma, M., and Ohashi, K. 2009. Cytokine profiles in chickens infected with virulent and avirulent Marek’s disease viruses: interferon-gamma is a key factor in the protection of Marek’s disease by vaccination. Microbiol. Immunol.53: 224-232. 

4 ) Kano, R., Konnai, S., Onuma, M., and Ohashi, K. 2009. Microarray analysis of host immune responses to Marek’s disease virus infection in vaccinated chickens. J. Vet. Med. Sci., 71: 603-610. 

5 ) Logullo, C., Witola, W.H., Andrade, C., Abreu, L., Gomes, J., da Silva Vaz, I. Jr., Imamura, S., Konnai, S., Ohashi, K., Onuma, M., 2009. Expression and activity of glycogen synthase kinase during vitellogenesis and embryogenesis of Rhipicephalus (Boophilus) microplusVet. Parasitol., 161: 261-269. 

6 ) Mingala, C. N., Konnai, S., Cruz, L. C., Onuma, M., and Ohashi, K. 2009. Comparative moleculo-immunological analysis of swamp and riverine type water buffaloes responsesCytokine, 46: 273-282. 

7 ) Konnai, S., Mekata, H., Mingala, C. N., Abes, N. S., Gutierrez, C. A., Herrera, J. R., Dargantes, A.P., Witola, W. H., Cruz, L. C., Inoue, N., Onuma, M., and Ohashi, K. 2009.Development and application of a quantitative real-time PCR for the diagnosis of Surra in water buffaloes. Infect. Genet. Evol., 9: 449-452. 

8 ) Imamura, S., da Silva Vaz, I. Jr., Konnai, S., Yamada, S., Najajima, C., Onuma, M., and Ohashi, K. 2009. Effect of vaccination with a recombinant metalloprotease fromHaemaphysalis longicornis. Exp. Appl. Acarol.48: 345-358. 

9 ) Saito, Y., Konnai, S., Yamada, S., Imamura, S., Nishikado, H., Ito, T., Onuma, M., and Ohashi, K. 2009. Identification and characterization of antimicrobial peptides, defensin, in the taiga tick Ixodes persulcatusInsect Mol. Biol., 18: 531-539. 

10) Mingala, C. N., Konnai, S., Venturina, A., Onuma, M., and Ohashi, K. 2009. Quantification of water buffalo (Bubalus bubalis) cytokine expression in response to inactivated foot-and-mouth disease (FMD) vaccineRes. Vet. Sci.,87: 213-217. 

11) Yamada, S., Konnai, S., Imamura, S., Simuunza, M., Chembensofu, M., Chota, A., Nambota, A., Onuma, M., and Ohashi, K. 2009. PCR-based detection of blood parasites in cattle and adult Rhipicephalus appendiculatus ticks. Vet. J., 182: 352-355. 

12) Mingala, C. N., Konnai, S., Onuma, M., and Ohashi, K. 2009. Classification of new BVDV isolates from Philippine water buffalo using the viral E2 regionJ. Basic Microbiol., 49: 495-500. 

13) Yamada, S., Konnai, S., Imamura, S., Ito, T., Onuma, M., and Ohashi, K. 2009. Cloning and characterization of Rhipicephalus appendiculatus voraxinalpha and its effect as anti-tick vaccineVaccine, 27: 5989-5997. 

14) Mekata, H., Konnai, S., Witola, W.H., Inoue, N., Onuma, M., and Ohashi, K. 2009.Molecular detection of trypanosomes in cattle in South America and genetic diversity of Trypanosoma evansi based on expression-site-associated gene 6.Infect. Genet. Evol.9: 1301-1305. 

15) Parizi, L. F., Rech, H., Ferreira, C. A., Imamura, S., Ohashi, K., Onuma, M., Masuda, A., and da Silva Vaz I. Jr. 2009. Comparative immunogenicity of Haemaphysalis longicornis and Rhipicephalus (Boophilus) microplus calreticulins. Vet. Parasitol.,164: 282-290. 

 

Publications other than original articles

 

1 ) Konnai, S., Tajima, M., Onuma, M., Ohashi, K. 2009. Current topics on Bovine leukemia virus infection and its control in the fieldJ. Hokkaido Vet. Med. Assoc.,53: 529-534. (in Japanese) 

 

2008

Original articles

 

1 ) Konnai, S., Mingala, C. N., Sato, M., Abes, N. S., Venturina, F. A., Gutierrez, C. A., Sano, T., Omata, Y., Cruz, L. C., Onuma, M., and Ohashi, K. 2008. A survey of abortifacient infectious agents in livestock in Luzon, the Philippines, with emphasis on the situation in a cattle herd with abortion problems. Acta Trop105: 269-273.

2 ) Odbileg, R., Purevtseren, B., Gantsetseg, D., Boldbaatar, B., Buyannemekh, T., Galmandakh, Z., Erdenebaatar, J., Konnai, S., Onuma, M., and Ohashi, K., 2008. Cytokine responses in camels (Camelus bactrianus) vaccinated withBrucella abortusstrain 19 vaccineJ. Vet. Med. Sci70: 197-201.

3 ) Hatai, H., Ochiai, K., Nagakura, K., Imanishi, S., Ochi, A., Kozakura, R., Ono, M., Goryo, M., Ohashi, K., and Umemura, T. 2008. A recombinant avian leukosis virus associated with fowl glioma in layer chickens in Japan. Avian Pathol37: 127-137.

4 ) Konnai, S., Saito, Y., Nishikado, H., Yamada, S., Imamura, S., Mori, A., Ito, T., Onuma, M., and Ohashi, K. 2008. Establishment of a laboratory colony of taiga tick Ixodes persulcatus for tick-borne pathogen transmission studies. Jpn. J. Vet. Res55: 85-92.

5 ) Hatai, H., Ochiai, K., Murakami, M., Imanishi, S., Tomioka, Y., Toyoda, T., Ohashi, K., and Umemura, T. 2008. Prevalence of fowl glioma-inducing virus in chickens of zoological gardens in Japan and nucleotide variation in the env geneJ. Vet. Med. Sci70: 469-474.

6 ) Konnai, S., Mekata, H., Odbileg, R., Simuunza, M., Chembensof, M., Witola, W. H., Tembo, M. E., Chitambo, H., Inoue, N., Onuma, M., and Ohashi, K. 2008. Detection of Trypanosoma brucei in field-captured Tsetse flies and identification of host species fed on by the infected flies. Vector Borne Zoonotic Dis., 8: 565-573.

7 ) Imamura, S., Konnai, S., da Silva, V. I. Jr., Yamada, S., Nakajima, C., Ito, Y., Tajima, T., Yasuda, J., Simuunza, M., Onuma, M., and Ohashi, K. 2008. Effects of anti-tick cocktail vaccine against Rhipicephalus appendiculatusJpn. J. Vet. Res56: 85-98.

8 ) Murao, T., Omata, Y., Kano, R., Murata, S., Okada, T., Konnai, S., Asakawa, M., Ohashi, K., and Onuma, M. 2008. Serological survey of Toxoplasma gondii in wild waterfowl in chukotka, Kamchatka, Russia and Hokkaido, JapanJ. Parasitol., 94: 830-833.

9 ) Yamada, S., Ito, Y., Imamura, S., Konnai, S., Ito, T., Onuma, M., and Ohashi, K. 2008.Rhipicephalus appendiculatus: Characterization of a testis-associated protein.Exp. Parasitol120: 337-342.

10) Mekata, H., Konnai, S., Simuunza, M., Chembensofu, M., Kano, R., Witola, W. H., Tembo, M. E., Chitambo, H., Inoue, N., Onuma, M., and Ohashi, K. 2008. Prevalence and source of Trypanosome infections in field-captured vector flies (Glossina pallidipes) in southeastern ZambiaJ. Vet. Med. Sci., 70: 923-928.

 

2007

Original Articles

 

1 ) Mingala, C. N., Odbileg, R., Konnai, S., Ohashi, K. and Onuma, M. 2007. Molecular cloning, sequencing and phylogenetic analysis of inflammatory cytokines of swamp type buffalo contrasting with other bubaline breeds. Comp. Immunol. Microbiol. Infect. Dis., 30: 119-131.

2 ) Usui, T., Konnai, S., Ohashi, K. and Onuma, M. 2007. Interferon-gamma expression associated with suppression of bovine leukemia virus at the early phase of infection in sheep. Vet. Immunol. Immunopathol., 115: 17-23.

3  )Murata, S., Chang, K-S., Yamamoto, Y., Okada, T., Lee, S-I., Konnai, S., Onuma, M., Osa, Y., Asakawa, M. and Ohashi, K. 2007. Detection of the Marek’s disease virus genome from feather tips of wild geese in Japan and the Far East region of Russia. Arch. Virol., 152: 1523-1526.

4 ) Okada, T., Takagi, M., Murata, S., Onuma, M. and Ohashi, K. 2007. Identification and characterization of a novel spliced form of the meq transcript in lymphoblastoid cell lines derived from Marek’s disease tumors. J. Gen. Virol., 88: 2111-2120.

5 ) Konnai, S., Yamada, S., Imamura, S., Simuunza, M., Chembensof, M., Chota, A., Nambota, A., Ohashi, K. and Onuma, M. 2007. Attachment Duration Required for Rhipicephalus appendiculatus to Transmit Theileria parva to the Host. Vector Borne Zoonotic. Dis., 7: 241-248.

6 ) Murata, S., Chang, K-S., Lee, S-I., Konnai, S., Onuma, M. and Ohashi. K. 2007. Development of a diagnostic method to detect oncogenic Marek’s disease virus (MDV) from feather tips. J. Vet. Diagnost. Invest., 19: 471-478.

 

Publications other than original articles

 

1 ) Imamura, S., Konnai, S., Ohashi, K. and Onuma, M. 2007. Recent topics of candidate antigens for immunological control of Ixodid ticks. Acta Sci. Vet., 35: 1-16.

 

2006

Original Articles

 

1 ) Konnai, S., Usui, T., Ikeda, M., Kohara, J., Hirata, T. , Okada, K., Ohashi, K. and Onuma, M. 2006. Tumor necrosis factor α up-regulation in spontaneously proliferating cells derived from bovine leukemia virus-infected cattle. Arch. Virol., 151: 347-360.

2 ) Imamura, S., Namangala, B., Tajima, T., Tembo, E. M., Yasuda, J., Ohashi. K. and Onuma, M. 2006. Two serine protease inhibitor(serpin)that induce a bovine protective immune response against Rhipicephalus appendiculatus ticks . Vaccine, 24: 2230-2237.

3 ) Nakajima, C., Imamura, S., Konnai, S., Yamada, S., Nishikado, H., Ohashi , K. and Onuma, M. 2006. A novel gene encoding a thrombin inhibitory protein in a cDNA library fromHaemaphysalis longicornis salivary gland. J. Vet. Med. Sci., 68: 447-452.

4 ) Tsuda, A. , Witola , W. H. , Konnai, S. , Ohashi, K. and Onuma, M. 2006. The effect of TAO expression on PCD-like phenomenon development and drug resistance in Trypanosoma brucei. Parasitol. Int., 55: 135-142.

5 ) Kohara, J., Konnai, S. and Onuma, M. 2006. Experimental transmission of Bovine leukemia virus in cattle via rectal palpation. Jpn. J. Vet. Res., 54: 25-30.

6 ) Takagi, M., Onuma, M. and Ohashi, K. 2006. The role of a short form of p53 in chicken lymphoblastoid cell lines during apoptosis. J. Vet. Med. Sci., 68: 561-566.

7 ) Takagi, M., Ohashi, K. and Onuma, M. 2006. The presence of the p53 transcripts with truncated open reading frames in Marek’s disease tumor-derived cell lines. Leukemia Res., 30: 987-992.

8 ) Usui , T. , Konnai , S. , Ohashi , K. and Onuma, M. 2006. Expression of tumor necrosis factor-α in IgM+ B-cells from bovine leukemia virus-infected lymphocytotic sheep. Vet. Immunol. Immunopathol., 112: 296-301.

9 ) Konnai, S., Usui, T., Ikeda, M., Kohara, J., Hirata, T. , Okada, K., Ohashi, K. and Onuma, M. 2006. Tumor necrosis factoralpha genetic polymorphism may contribute to progression of bovine leukemia virus-infection. Microb. Infect., 8: 2163-2171.

10) Odbileg, R., Purevtseren, B., Batsukh, Z., Konnai, S., Ohashi, K. and Onuma, M. 2006. Complete cDNA sequences and phylogenetic analysis of Th1 and Th2 cytokines of bactrian camel(Camelus bactrianus). J. Vet. Med. Sci., 68: 941-946.

11) Konnai, S., Imamura, S., Nakajima, C., Witola,W. H., Yamada, S., Simuunza, M., Nambota, A., Yasuda, J., Ohashi, K. and Onuma, M. 2006. Acquisition and transmission of Theileriaparva by vector tick, Rhipicephalus appendiculatus. Acta Trop., 99: 34-41.

12) Mingala, C. N., Odbileg, R., Konnai, S., Ohashi, K. and Onuma, M. 2006. Comparative assessment of Th1 and Th2 cytokines of swamp type buffalo and other bubaline breeds by molecular cloning, sequencing and phylogenetics. Vet . Immunol. Immunopathol., 113: 348-356.

 

Publications other than original articles

 

1 ) Onuma, M. and Igimi, M. 2006. Various recognition of foreign antigens and microbial infectious. J. Vet. Med., 59: 553-554. (in Japanese).

2 ) Nakajima , C . and Onuma , M. 2006. Search for variable biological molecules derived from tick salivary glnd‐‐development of new anti-tick vaccine‐‐. J. Vet. Med., 59: 735-742. (in Japanese).

3 ) Onuma, M. 2006. Infection and Infectious diseases(General Introduction), bovine leukosis and Maedi-visna virus infection, et al. In : Infectious Diseases of Animals, Onuma, M. et al eds., pp.2-46, 62-67, 76-90, 110. (in Japanese).

4 ) Ohashi, K. 2006. Marek’s diseases, Avian leukosis, Egg drop syndrome 1976, et al. In : Infectious Diseases of Animals , Onuma, M. et al eds., pp.204-205, 210, 212. (in Japanese).

 

2005

Original Articles

 

1 ) Witola, W.H., Inoue, N., Ohashi, K. and Onuma, M. 2005. Genetic variability in ESAG6 genes among Trypanosoma evansi isolates and in comparison to
other Trypanozoon members. Acta. Trop.,93: 63-73.

2 ) da Silva Vaz, I. Jr., Imamura, S., Nakajima, C., de Cardoso, F. C., Ferreira, C.A.S., Renard, G., Masuda, A., Ohashi, K. and Onuma, M. 2005. Molecular cloning and sequence analysis of cDNAs encoding for Boophilus microplus , Haemaphysalis longicornis and Rhipicephalus appendiculatus actins. Vet. Parasitol., 127: 147-155.

3 ) Imamura, S., Itabajara, S.V., Sugino, M., Ohashi, K. and Onuma, M. 2005. A serine protease inhibitor (serpin) from Haemaphysalis longicornis as an anti-tick vaccine. Vaccine, 23: 1301-1311.

4 ) Odbileg, R., Konnai, S., Usui, T., Ohashi, K. and Onuma, M. 2005. Quantification of llama inflammatory cytokine mRNAs by real-time RT-PCR. J.Vet. Med. Sci., 67: 195-198.

5 ) Toyoda , T. , Ochiai , K . , Ohashi , K. , Tomioka, T., Kimura, T. and Umemura, T. 2005. Multiple perineuriomas in chicken (Gallus gallus domesticus). Vet. Pathol., 42: 176-183.

6 ) Odbileg, R., Lee, S.I., Yoshida, R., Chang, K.S., Ohashi, K. and Onuma, M. 2005. Cloning and sequence analysis of llama (lama glama) Th2 (IL‐4, IL-10 and IL-13) cytokines. Vet. Immunol. Immunopathol., 104: 145-153.

7 ) Kozasa, T., Tajima,M., Yasutomi, I., Sano, K., Ohashi, K. and Onuma, M. 2005. Relationship of bovine diarrhea virus persistent infection to incidence of diseases on dairy farms based on bulk tank milk test by RT-PCR. Vet.Microbiol., 106: 41-47.

8 ) Pham, H.M., Nakajima, C., Ohashi, K. and Onuma, M. 2005. Loop-mediated isothermal amplification for rapid detection of Newcastle disease virus. J. Clin. Microbiol., 43: 1646-1650.

9 ) Ohya, K., Matsumura, T. , Itchoda, N. , Ohashi, K., Onuma, M. and Sugimoto, C. 2005. Ability of orally administered IFN-alpha-containing transgenic potato extracts to inhibit Listeria monocytogenes infection. J. Interferon Cytokine Res., 25: 459-466.

10) Chang, K-S., Ohashi, K., Lee, S.-I., Takagi, M. and Onuma, M. 2005. Detection of the meq gene in the T cell subsets from chickens infected with Marek’s disease virus serotype1. Jpn. J. Vet. Res., 53: 3-11.

11) Tsuda, A., Witola, W. H., Ohashi, K. and Onuma, M. 2005. Expression of alternative oxidase inhibits programmed cell death-like phenomenon in bloodstream form of Trypanosoma brucei rhodesiense. Parasitol. Int., 54: 243-251.

12) Konnai, S., Usui, T., Ikeda, M., Kohara, J., Hirata, T.I., Okada, K., Ohashi, K. and Onuma, M. 2005. Imbalance of tumor necrosis factor receptors during progression in bovine leukemia virus infection. Virology, 339: 239-248.

13) He, W. , Ohashi , K. , Sugimoto, C. and Onuma, M. 2005. Cloning and characterization of cDNA encoding a prohibitin-like protein from Theileria orientalis. Jpn. J. Vet. Res., 53: 27-35.

14) Odbileg, R., Konnai, S., Ohashi, K. and Onuma, M. 2005. Molecular cloning and phylogenetic analysis of inflammatory cytokines of Camelidae (llama and camel). J. Vet. Med. Sci., 67: 921-925.

15) He, W. , Ohashi , K. , Sugimoto, C. and Onuma , M. 2005. Theileria orientalis : Cloning a cDNA encoding a protein similar to thiol protease with haemoglobinbinding activity. Exp. Parasitol., 111: 143-153.

16) Witola,W.H., Tsuda, A., Inoue, N., Ohashi, K. and Onuma, M. 2005. Acquired resistance to berenil in a cloned isolate of Trypanosoma evansi is associated with upregulation of a novel gene, TeDR40. Parasitology, 131: 635-646.

17) Ikeda , M. , Konnai , S. , Onuma , M. , Ishiguro , N. , Goryo , M. and Okada , K. 2005. Immunohistochemical analysis of expression patterns of tumor necrosis factor receptors on lymphoma cells in enzootic bovine leukosis. J. Vet. Med. Sci., 67: 425-432.

18) Nakamura, K., Sakamoto, K., Kido, Y., Fujimoto, Y., Suzuki, T., Suzuki, M., Yabu, N., Ohta, N., Tsuda, A., Onuma, M. and Kita, K. 2005. Mutational analysis of the Trypanosoma vivaxalternative oxidase : the E(X) 6Y motif is conserved in both mitochondrial alternative oxidase and plastid terminal oxidase and is indispensable for enzyme activity. Biochem. Biophys. Res. Commun., 334: 593-600.

19) Pham, H.M., Konnai, S., Usui, T., Chang, K-S., Murata, S., Mase, M., Ohashi, K. and Onuma,M. 2005. Rapid detection and differentiation of Newcastle disease virus by real-time PCR with melting-curve analysis. Arch. Virol., 150: 2429-2438.

20) Nakajima, C., Da Siva Vaz, I., Imamura, S., Konnai, S., Ohashi, K. and Onuma, M. 2005. Random sequencing of cDNA library derived from partially-fed adult female Haemaphysalis longicornis salivary gland. J. Vet. Med. Sci., 67: 1127-1131.

21) Okada, K., Nakane, N., Kuramochi, K., Yin, S.A., Takami, S., Hirata, T., Goryo, M., Numakunai, S., Takeshima, S.N., Takashima, M., Tajima, S., Konnai, S., Onuma, M. and Aida, Y. 2005. Bovine leukemia virus high tax molecular clone experimentally induces leukemia / lymphoma in sheep. J. Vet. Med. Sci., 67: 1231-1235.

22) Ozawa , M. , Ohashi , K. and Onuma , M. 2005. Identification and characterization of peptides binding to Newcastle disease virus by phage display. J. Vet. Med. Sci., 67: 1237-1241.

23) Hatai, H., Ochiai, K., Tomioka, Y., Toyoda, T., Hayashi, K., Toda, K., Ohashi, K., Ono, E., Kimura, T. and Umemura, T. 2005. Nested polymerase chain reaction fro detection of the avian leucosis virus causing so-called fowl glioma. Avian Pathol., 34: 473-479.

 

Publications other than original articles

 

1 ) Onuma, M. 2005. Bovine leukemia . In : Biosecurity in dairy farms(Nagahata, H. ed.)pp.100-105. Research & Development Center for Dairy Farming. (in Japanese).

2 ) Onuma, M. 2005. Vaccine-induced immunity against infectious diseases. In:Dairy Journal pp.20-23. Rakuno Gakuen University Extension Center (in Japanese).

 

2004

Original Articles

 

1 ) Odbileg, R., Lee, S. I., Yoshida, R., Chang, K. S., Ohashi, K., Sugimoto, C., and Onuma, M. 2004. Cloning and sequence analysis of llama cytokines related to cell-mediated immunity. Vet Immunol. Immunopathol., 102:93-102.

 

2 ) Pham, H. M., Chang. K. S., Mase, M., Ohashi, K., and Onuma, M. 2004. Molecular characterization of the nucleocapsid protein gene of Newcastle disease virus strains in Japan and development of a restriction enzyme-based rapid identifying method. Arch. Virol.,149:1559-1569.

 

3 ) Meas, S., Nakayama, M., Usui, T., Nakazato, Y., Yasuda, J., Ohashi, K., and Onuma, M. 2004. Evidence for bovine immunodeficiency virus infection in cattle in Zambia. Jpn. J. Vet. Res., 52:3-8.

 

4 ) Witola, W. H., Inoue, N., Ohashi, K., and Onuma, M. 2004. RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate. Exp. Parasitol., 107:47-57.

 

5 ) Silva Vaz, Jr. I., Imamura, S., Ohashi, K., and Onuma, M. 2004. Cloning, expression and partial characterization of a Haemaphysalis longicornis and a Rhipicephalus appendiculatus glutathione S-transferase. Insect. Mol. Biol., 13:329-335.

 

6 ) Tomioka, Y., Ochiai, K., Ohashi, K., Ono, E., Toyoda, T., Kimura, T., and Umemura, T. 2004. Genome sequence analysis of the avian retrovirus causing so-called fowl glioma and the promoter activity of the long terminal repeat. J. Gen. Virol., 85:647-652.

 

7 ) Fujimoto, W., Kimura, K., Suzuki, M., Syuto, B., Onuma, M., and Iwanaga, T. 2004. Quantitative changes in serum concentration of bovine gut chitinase in Theileria infection. J. Vet. Med. Sci., 66:291-294.

 

8 ) Takahashi, M., Tajima, S., Takeshima, S. N., Konnai. S., Yin, S. A., Okada, K., Davis, W. C., and Aida, Y. 2004. Ex vivo survival of peripheral blood mononuclear cells in sheep induced by bovine leukemia virus (BLV) mainly occurs in CD5- B cells that express BLV. Microbes. Infect., 6:584-595.

 

9 ) Kozasa, T., Tajima, M., Ohashi, K. and Onuma, M. 2004. Surveillance of bovine viral-diarrhea virus infection in diseased cattle. J. Jpn. Vet. Med. Assoc., 57(8) : 511-514 (in Japanese).

 

10) Kozasa, T., Tajima, M., Sano, K., Yasutomi, I., Ohashi, K. and Onuma, M. 2004. detecting the veutralizing antibody in bulk-milk whey to investigate prevalence of infection with the bovine viral-diarrhea virus. J. Jpn. Vet. Med. Assoc., 57(11) : 705-709 (in Japanese).

 

Publications other than original articles

 

1 ) Onuma, M. 2004. Control of infectious diseases by vaccination. Small Animal Clinic, 137 : 11-19 (in Japanese).

 

2 ) Onuma, M., Imamura, S. and Nakajima, C. 2004. Development of anti-tick vaccine. J. Vet. Med., 57(9): 753-757 (in Japanese).

 

3 ) Ohashi, K., Chang, K. S., Lee, S. L., Murata, S., Takagi, M., and Onuma, M. 2004. The roles of the L-meq gene and its gene product the latent infection and transformation by Mareck's disease virus. ibid. 57: 597-595 (in Japanese).

 

4 ) Onuma, M. 2004. BLV infection and pathogenesis of BLV. J. Clinic. Vet. Med., 22 : 10-14 (in Japanese).

 

5 ) Onuma, M. 2004. Transmission and clearanse of BLV infection in herds. ibid. 22 : 15-19 (in Japanese).

 

6 ) Konnai, S. 2004. Genetic resistance in BLV infection. ibid. 22 : 20-23 (in Japanese).

 

7 ) Onuma, M. 2004. Immunology and vaccine programs of kitten and puppy. InfoVets. 7 : 11-17 (in Japanese).

 

8 ) Onuma, M. 2004. Fight against vector ticks : Development of anti-tick vaccine. Littera Populi, 20 : 12 (in Japanese).

 

2003

Original Articles

 

1 ) Usui, T., Meas, S., Konnai, S., Ohashi, K., Onuma, M. 2003. Seroprevalence of bovine immunodeficiency virus and bovine leukemia virus in dairy and beef cattle in Hokkaido. J. Vet. Med. Sci. 65(2):287-289.

 

2 ) Sarataphan, N., Kakuda, T., Chansiri, K., Onuma, M. 2003. Survey of benign Theileria parasites of cattle and buffaloes in Thailand using allele-specific polymerase chain reaction of major piroplasm surface protein gene. J. Vet. Med. Sci. 65(1): 133-135.

 

3 ) Tajima, S., Takahashi, M., Takeshima, S., Konnai, S., Yin, S.A., Watarai, S., Tana, Tanaka, Y., Onuma, M., Okada, K., Aida, Y. 2003. A mutant form of the of bovine leukemia virus (BLV), with enhanced transactivation activity, increases expression and propagation of BLV in vitro but not in vivo. J. Virol. 77(3):1894-1903.

 

4 ) Nakajima, M., Yanase, H., Iwanaga, T., Kodama, M., Ohashi, K., Onuma, M. 2003. Passive immunization with monoclonal antibodies : effects on Haemaphysalis longicornis tick infestation of BALB/c mice. Jpn. J. Vet. Res. 50(4):157-163.

 

5 ) Suginon, M., Imamura, S., Mulenga, A., Nakajima, M., Tsuda, A., Ohashi, K., Onuma, M. 2003. A serine proteinase inhibitor (serpin) from ixodid tick Haemaphysalis longicornis; cloning and preliminary assessment of its suitability as a candidate for a tick vaccine. Vaccine, 21:2844-2851.

 

6 ) Mulenga, A., Tsuda, A., Onuma, M., Sugimoto, C. 2003. Four serine proteinase inhibitor (serpin) from brown ear tick, Rhipicephalus appendiculatus: cDNA cloning and preliminary characterization. Insect Biochem. Mol. Biol. 33:267-276.

 

7 ) Mulenga, A., Onuma, M., Sugimot, C. 2003. Three serine proteinases from midgets of the hard tick Rhipicephalus appendiculatus: cDNA cloning and preliminary characterization. Exp. Applied Acarology 29:151-164.

 

8 ) Zhou, J., Yamasaki, M., Ohashi, K., Onuma, M. 2003. cDNA cloning of a Rab5 homologue in Babesia gibsoni. J. Vet. Med. Sci. 65(4):519-521.

 

9 ) Mweene, A. S., Fukushi, H., Pandy, G. S., Syakalima, M., Simuunza, M., Malamo, M., Nambota, A., Samui, K. L., Tsubota, Y., Nakazato, Y., Onuma, M., Yasuda, J. 2003. Prevalence of bovine herpesvirus 1 in traditional cattle in Southern province, Zambia. Scientific and Technical Review 22(3): 873-877.

 

10) Meas, S., Yilmaz, Z., Usui, T., Serhat Torum, Kadir Yesilbag, Ohashi, K., Onuma, M . 2003. Evidence for the presence of bovine immunodeficiency virus in cattle in Turkey. Jpn. J. Vet. Res. 51(1):3-8.

 

11) Konnai, S., Usui, T., Ohashi, K., Onuma, M. 2003. The rapid quantitative analysis of bovine cytokine genes by real-time RT-PCR. Vet. Microbiol. 94:283-294.

 

12) Nakajima, M., Kodama, M., Yanase, H., Iwanaga, T., Mulenga, A., Ohashi, K., Onuma, M. 2003. Production and characterization of monoclonal antibodies against midgnt of ixodid tick Haemaphysalis longicornis. Vet. Parasitol. 115:355-363.

 

13) Usui, T., Konnai, S., Tajima, S., Watarai, S., Aida, Y., Ohashi, K., Onuma, M. 2003. Protective effects vaccination with bovine leukemia virus (BLV) tax DNA against BLV infection in Sheep. J. Vet. Med. Sci. 65(11):1201-1205.

 

14) Konnai, S., Nagaoka, Y., Takeshima, S., Onuma, M., Aida, Y. 2003. Sequences and diversity of 17 new Ovar-DRB1 alleles from three breeds of sheep. Eurp. J. Immunogenetic. 30:275-282.

 

15) Konnai, S., Nagaoka, Y., Takeshima, S., Onuma, M., Aida, Y. 2003. Technical Note: DNA typing for Ovine MHC DRB1 using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). J. Dairy Sci. 86:3362-3365.

 

16) Tomioka, Y., Ochiai, K, Ohashi, K., Kimura, T., and Umemura, T.  2003. Inovo infection with an avian leukosis virus causing fowl glioma: viral distribution and pathogenesis.  Avian Pathol. 32: 617-624.

 

Publications other than original articles

 

1 ) 小沼 操.2003.開業獣医師のための免疫学,動物の生体防御:Ⅶ. ウイルス感染に対する防御. Small Animal Clinic  130: 4-12.

 

2 ) 小沼 操.2003.(水曜インタビュー)BSE発生2年半、いまとこれからを考える.北海協同組合通信 13302:1-7.

 

3 ) 小沼 操.2003.ペットを介する人の病気について~人獣共通感染症~.キャリアエイジマガジン 40歳からの仕事 (株)北海道アルバイト情報社, 121[5.22]:14.

 

4 ) 小沼 操.2003.ペットを介する人の病気.健康さっぽろ社)札幌市医師会,9: 1.

 

5 ) 小沼 操.2003.ペットからうつる病気…知っておきたい人獣共通感染症….暮らしと健康の月刊誌ケア 6月号:40-43.

 

6 ) 岡田信彦,小沼 操.2003.病原微生物の宿主感染機構と病原性「緒言」.獣医畜産新報  56(7): 595-596.

 

7 ) 小沼 操.2003.開業獣医師のための免疫学,動物の生体防御:Ⅷ. 原虫感染に対する防御. Small Animal Clinic  132: 4-10.

 

8 ) 小沼 操.2003.国際開発協力とは何か.日獣会誌 56: 695-696.

 

9 ) Onuma, M., Imamura., S, Nakajima., C. 2003. Control of Tick-transmitted Infectious diseases by anti-tick vaccine. Joint symposium between Hokkaido University Graduate School of Veterinary Medicine and Seoul national University College of Veterinary medicine, Second COE International Symposium for Zoonosis Control. Dec. 5, 2003:57-59.

 

10) 小沼 操.2003.開業獣医師のための免疫学,動物の生体防御:Ⅸ. 犬猫のウイルス感染症に対する防御. Small Animal Clinic  133: 4-12.

 

11) 岡田幸助,尹 善愛,池田 学,今内 覚,田島 茂,竹嶋伸之輔,高橋雅彦,平田統一,沼宮内 茂,御領政信,小沼 操,間 陽子.2003.御明神牧場 におけるウシ白血病ウイルス接種実験概要. 岩手大学農学部附属寒冷フィールドサイエンス教育研究センター年報別刷:p69-78.

 

12) 小沼 操,川本 哲,畠山英樹,大橋和彦.2003.ダニ由来分子を用いた抗ダニワクチンによるダニ媒介性伝染病の防除.ノーステック財団 研究開発助成事業 平成14年度研究成果報告書:p59.

 

13) 大橋和彦.2003. イリドウイルスと感染症. 獣医微生物学 (見上彪監修)文永堂出版(株)p201-203.

 

2002

Original Articles

 

1 ) Meas, S., Usui, T., Ohashi, K., Sugimoto, C., Onuma, M. 2002. Vertical transmission of bovine leukemia virus and bovine immunodeficiency virus in dairy cattle herds. Vet. Microbiol. 84: 275-282.

 

2 ) Ohya, K., Itchoda, N., Ohashi, K., Onum, M., Sugimoto, C., Matsumura, T. 2002. Expression of biologically active human tumor necrosis factor-a in transgenic potato plant. J. Interferon Cytokine Res. 22:371-378.

 

3 ) Chang, K. C., Lee, S-I., Ohashi, K., Ibrahim, A., Onuma, M. 2002. The detection of the meq gene in chicken infected with Marek’s disease virus serotype 1. J. Vet. Med. Sci. 64(5), 413-417.

 

4 ) Meas, S., Ruas, F. J., Usui, T., Teraoka, Y., Mulenga, A., Chang, K-S., Masuda, A., Madruga, C. R., Ohashi, K., Onuma, M. 2002. Seroprevalence and molecular evidence for the presence of bovine immunodeficiency virus in Brazilian cattle. Jpn. J. Vet. Res. 50(1):9-16.

 

5 ) Chang, K-S., Ohashi, K., Onuma, M. 2002. Diversity (polymorphism) of the meq gene in the attenuated Marek’s disease virus (MDV) serotype 1 and MDV-transformed cell lines. J. Vet. Med. Sci. 64(12): 1097-1101.

 

6 ) Chang, K-S., Ohashi, K., Onuma, M. 2002. Suppression of transcription activity of the MEQ protein of oncogenic Marek’s disease virus serotype 1 (MDV1) by L-MEQ of non-oncogenic MDV1. J. Vet. Med. Sci. 64(12): 1091-1095.

 

7 ) Zhou, J., Mulenga, A., Yamasaki, M., Ohashi, K., Maede, Y., Onuma, M. 2002. Babesia gibsoni : Molecular cloning and characterization of Rab6 and Rab11 homologues. Experimental Parasitol. 101: 210-214.

 

8 ) Iwata, N., Ochiai, K., Hayashi, K., Ohashi, K., and Umemura, T. 2002. Nonsuppurative myocarditis associated with so-called fowl glioma. J. Vet.Med. Sci. 64: 395-399.

 

9 ) Iwata, N., Ochiai, K., Hayashi, K., Ohashi, K., and Umemura, T. 2002. Avian retrovirus infection causes naturally occurring glioma: isolation and transmission of a virus from so-called fowl glioma. Avian Pathol 31: 193-199.

 

Publications other than original articles

 

1 ) Mulenga, A., Tsuda, A., Sugimoto, C., Onuma., M. 2002. Blood meal acquisition by tick; Molecular advances and implication for vaccine development. Jpn. J. Vet. Res. 49(4):261-272.

 

2 ) 小沼 操.2002.開業獣医師のための免疫学,動物の生体防御:IV. 特異的な獲得免疫. Small Animal Clinic 126: 4-13.

 

3 ) 小沼 操.2002.牛海綿状脳症(BSE)と研究の現状.フロンティア180 41:18-23.北海道町村会.

 

4 ) 小沼 操.2002.牛海綿状脳症(BSE)と研究の現状. 北獣会誌, 46:5-10.

 

5 ) 小沼 操.2002.家畜伝染病の防疫と危機管理. 獣医畜産新報,  55(5):385-390.

 

6 ) 小沼 操.2002.開業獣医師のための免疫学,動物の生体防御:V.感染症に対する生体防御. Small Animal Clinic  127: 4-13.

 

7 ) Onuma, M. 2002. 牛海綿状脳症 (BSE). 主要症状を基礎にした牛の臨床.(前出吉光,小岩政照監修)ディリーマン,pp448-451.

 

8 ) Onuma, M., Kakuda, T. 2002. リステリア症. 主要症状を基礎にした牛の臨床.(前出吉光,小岩政照監修)ディリーマン,pp452-454

 

9 ) Onuma, M. 2002. ヘモフィルス・ソムナス感染症.主要症状を基礎にした牛の臨床.(前出吉光,小岩政照監修)ディリーマン, pp459-462.

 

10) Onuma, M. 2002. 牛のクラミジア症.主要症状を基礎にした牛の臨床.(前出吉光,小岩政照監修)ディリーマン, pp477-479

 

11) Onuma, M. and Kakuda, T. 2002. 伝染性角結膜炎(ピンクアイ).主要症状を基礎にした牛の臨床.(前出吉光,小岩政照監修)ディリーマン, pp620-621.

 

12) Ibrahim, A.I.A., Mubarak, M., Chan, K-S., Ohashi, K., Onuma, M. 2002. Biological and pathological studies on Marek’s disease virus (strains MD5 and CVI-998C/R6) using polymerase chain reaction (PCR). 1st Int. Sci. Conf. Fac. Vet. Med. 10-11 March 2002-South Valley Univ., Oena-EGYPT, p1-13.

 

13) Ohashi, K., Chan, K-S., Ibrahim, A.I.A., Lee, S., Onuma, M. 2002. The L-meq gene detected in chicken cells infected with Marek’s disease virus serotype 1. 1st Int. Sci. Conf. Fac. Vet. Med. 10-11 March 2002-South Valley Univ., Oena-EGYPT, p21-26.

 

14) 小沼 操.2002.開業獣医師のための免疫学,動物の生体防御:Ⅵ. 細菌、リケッチャ、真菌感染に対する防御. Small Animal Clinic 129: 4-13.

 

15) 大橋和彦.2002. マレック病.動物の感染症.(清水悠紀臣ら編)近代出版(株),pp252-254.

 

16) 大橋和彦.2002. トリ白血病・肉腫.動物の感染症.(清水悠紀臣ら編)近代出版(株), pp258-260.

 

2001

Original Articles

 

1 ) Iwasaki, T., Tnaka, A., Itakura, A., Yamasita, N., Ohta, K., Matsuda, H., Onuma, M. 2001. Atopic NC/Nga mice as a model for allergic asthma: Severe allergic responses by single intranasal challenge with protein antigen. J. Vet. Med. Sci. 63(4): 413-419.

 

2 ) Lee, S-I., Ohashi, K., Sugimoto, C., Onuma, M. 2001. Heparin inhibits plaque formation by cell-free Marek's disease viruses in vitro. J. Vet. Med. Sci. 63(4): 427-432.

 

3 ) Iwasaki, T., Tnaka, A., Matsuda, H., Onuma, M. 2001. Atopic NC/Nga mice as a model for allergic asthma: Cytokine profiles and eosinophil productivity of bone marrow. J. Vet. Med. Sci. 63(4): 471-474.

 

4 ) Mulenga, A., Sugimoto, C., Ingram, G., Ohashi, K., Onuma, M. 2001. Characterization of two cDNAs encoding serine proteinases from the hard tick Haemaphysalis longicornis. Insect Biochem. Mol. Biol. 31: 817-825.

 

5 ) Tana, Watarai, S., Aida, Y., Tajima, S., Kakidan,i H., Onuma, M., Kodama, H. 2001. Growth inhibition of cancer cells by co-transfection of diphtheria toxin A-chain gene plasmid with bovine leukemia virus-tax expression vector. Microbiol. Immunol. 45(6): 447-455.

 

6 ) Tsuda, A., Mulenga, A., Sugimoto, C., Nakajima, M., Ohashi, K., Onuma, M. 2001. cDNA cloning, characterization and vaccine effect analysis of Haemaphysalis longicornis tick saliva proteins. Vaccine 19: 4287-4296.

 

7 ) Ohya, K., Matsumura, T., Ohashi, K., Onuma, M., Sugimoto, C. 2001. Expression of two subtypes of human IFN-a in transgenic potato plants. J. Interferon Cytokine Res. 21: 595-602.

 

8 ) Kakuda, T., Sugimoto, C., Onuma, M. 2001. Epitope-mapping of antigen-specific T lymphocyte in cattle immunized with recombinant major piroplasm surface protein of Theileria sergenti. J. Vet. Med. Sci. 63(8): 895-901.

 

9 ) Inoue, M., Nguyen, D.V,, Meas, S., Ohashi, K,, Sen, S., Sugimoto, C., Onuma, M. 2001. Survey of Theileria parasite infection in cattle in Cambodia and Vietnam using piroplasm surface protein gene-specific polymerase chain reaction. J. Vet. Med. Sci. 63(10): 1155-1157.

 

10) Kabeya, H., Fukuda, A., Ohashi, K., Sugimoto, C., Onuma, M. 2001. Tumor necrosis factor and its receptors in experimentally bovine leukemia virus-infected sheep. Vet. Immunol. Immunopathol. 81: 129-139.

 

11) Syakalima, M. S., Choongo, K-C., Chilonda, P., Ahmadu, B., Mwase, M., Onuma, M., Sugimoto, C., Tsubota, T., Fukushi, H., Yoshida, M., Itagaki, T., Yasuda, J., Nakazato, Y. 2001. Bioaccumulation of lead in wildlife dependent on the contaminated environment of the Kafue flats. Bull. Environ. Contam. Toxicol. 67: 438-445.

 

Publications other than original articles

 

1 ) 小沼 操.2001.開業獣医師のための免疫学,動物の生体防御:II. 免疫はどのように発達してきたか. Small Animal Clinic 122: 4-17.

 

2 ) 小沼 操.2001).開業獣医師のための免疫学,動物の生体防御:III. 自然免疫から獲得免疫へ.Small Animal Clinic 123: 4-10.

 

3 ) 小沼 操,ムレンガ・アルバート,中島美枝,津田明子,杉野麻衣子.2001.ダニの分子を用いたダニ媒介性感染症の予防-抗ダニワクチンの開発-.動薬研究 61:11-22.

 

4 ) Kabeya, H., Ohashi, K., Onuma, M. 2001. Host immune responses in the course of bovine leukemia virus infection. J. Vet. Med. Sci. 63(7): 703-708.

 

5 ) Mulenga, A., Sugino, M., Nakajima, M., Sugimoto, C., Onuma, M. 2001. Tick-Encoded serine proteinase inhibitors (Serpins); Potential target antigens for tick vaccine development. J. Vet. Med. Sci. 63(10): 1063-1069.

 

6 ) 小沼 操,田島朋子. 2001.イヌとネコの免疫学的特性:「動物の免疫学」,pp142-150(小沼 操ら編著).文永堂出版.

 

7 ) 小沼 操. 2001.感染免疫:「動物の免疫学」,pp151-160(小沼 操ら編著).文永堂出版.

 

8 ) 小沼 操. 2001.腫瘍免疫:「動物の免疫学」,pp163-166(小沼 操ら編著).文永堂出版.

 

2000

Original Articles

 

1 ) Lee, S-I., Takagi, M., Ohashi, K., Morimura, T., Sugimoto, C., Onuma, M. 2000. Difference in the meq gene between oncogenic and attenuated strains of Marek's disease virus serotype 1. J. Vet. Med. Sci. 62(3): 287-292.

 

2 ) Meas, S., Seto, J., Sugimoto, C., Bakhsh, M., Riaz, M., Sato, T., Naeem, K., Ohashi, K., Onuma, M. 2000. Infection of bovine immunodeficiency virus and bovine leukemia virus in water buffalo and cattle populations in Pakistan. J. Vet. Med. Sci. 62(3):329-331.

 

3 ) Meas, S., Ohashi, K., Tum, S., Chhin, M., Te, K., Miura, K., Sugimoto, C., Onuma, M. 2000. Seroprevalence of bovine imunodeficiency virus and bovine leukemia virus in draught animal in Cambodia. J. Vet. Med. Sci. 62(7):779-781.

 

4 ) Mulenga, A., Sugimoto, C., Ohashi, K., Onuma, M. 2000. Characterization of an 84 kDa protein inducing an immediate hypersensitivity reaction in rabbits sensitized to Haemaphysalis longicornis ticks. Biochem. Biophys. Acta 1501: 219-226.

 

5 ) 趙 宏坤, 藤井城一, 壁谷英則, 菊池直哉, 高橋樹史, 小沼操. 2000. Effect of a special vaccination site on immune responses in sheep. Chinese J. Prevent. Vet. Med. 22(4): 276-274.

 

6 ) Meas, S., Ohashi ,K., Sugimoto, C., Onuma, M. 2000. Phylogenetic relationships of bovine imunodeficiency virus in cattle and buffaloes based on surface envelope gene sequences. Archiv. Virol. 146: 1037-1045.

 

7 ) Caccio, S., Camma, C., Onuma, M., Severini, C. 2000. The b-tubulin gene of Babesia and Theileria parasites is a informative marker for species discrimination. Int. J. Parasitol. 30: 1181-1185.

 

Publications other than original articles

 

1 ) 小沼 操,メアス ソティ.2000.ウシ白血病ウイルスの伝播.家畜診療 47(3):163-173.

 

2 ) Mulenga, A., Sugimoto, C., Nakajima, M., Ohashi, K., Onuma, M. 2000. Ticke saliva proteins interacting with the host immune response factors. Proceedings of the International Veterinary Cytokine and Vaccine Conference. March 16-17, 2000, Tsukuba, Japan, pp93-96.

 

3 ) Ohya, K., Matsumura, T., Sugimoto, C., Ohashi, K., Onuma, M. 2000. Expression of biologically active molecules in transgenic potatoes. Proceedings of the International Veterinary Cytokine and Vaccine Conference. March 16-17, 2000, Tsukuba, Japan, pp116-119.

 

4 ) Kabeya, H., Fukuda, A., Higuchi, T., Ohashi, K., Sugimoto, C., Onuma, M. 2000. Involvement tumor necrosis factor α in the pathogenesis of bovine leukemia virus infection. Proceedings of the International Veterinary Cytokine and Vaccine Conference. March 16-17, 2000, Tsukuba, Japan, pp155-158.

 

5 ) Aida, Y., Takesima, S., Nagaoka,Y., Ikegami, M., Gotoh-Inabe, K., Kabeya, H, Onuma, M., Okada, K. 2000. The relationship between polymorphism of the MHC class II DR gene and resistance and susceptibility to bovine leukemia virus-induced lymphoma. Proceedings of the International Veterinary Cytokine and Vaccine Conference. March 16-17, 2000, Tsukuba, Japan, pp159-162.

 

6 ) Okada, K., Sonoda, K., Koyama, M., Goryo, M., Kabeya, H., Onuma, M., Ohishi, K., Amanuma, H. 2000. Delayed-Type hypersensitivity in Sheep induced by synthetic peptides of bovine leukemia virus encapsulated in mannan-coated liposome. Proceedings of the International Veterinary Cytokine and Vaccine Conference. March 16-17, 2000, Tsukuba, Japan, pp197-200.

 

7 ) 小沼 操,小野悦郎,大屋賢司.2000.獣医学領域におけるバイオテクノロジーの展開?過去から21世紀に向けて?.獣医畜産新報 53(4):325-328.

 

8 ) Mulenga, A., Sugimoto, C., Onuma, M. 2000. Issues in tick vaccine development: identification and characterization of potential candidate vaccine antigens.  Microbes and Infection 2: 1353-1361.

 

9 ) 犬丸茂樹,小沼 操.2000.特集:21世紀に向けての獣医学- 微生物学からのアプローチ- 緒言. 獣畜産新報.  53(7):561-562.

 

10) 小沼 操.2000.狂牛病と人の病気:21世紀・新しい「いのち」像,pp83-103(馬渡峻輔,木村 純 編著).北海道大学.

 

11) 小沼 操.2000.開業獣医師のための免疫学,動物の生体防御:I. 動物はどのようにして感染症から身を守るのか. Small Animal Clinic  120: 4-14.

 

12) Mulenga, .A, Sugimoto, C., Onuma, M. 2000. Issues in tick vaccine development: identification and characterization of potential candidate vaccine antigens. Microbes and Infection 2: 1-9.

 

1999

Original Articles

 

1 ) Nagaoka, Y., Kabeya, H., Onuma, M., Kasai, N., Okada, K., and Aida, Y. 1999. Ovine MHC class 11 DRB I alleles associated with resistance or susceptibility to development of bovine leukemia virus-induced ovine lymphoma. Cancer Res ., 59, 975-981.

 

2 ) Kodama, H., Arimitsu, H., Mukamoto, M., and Sugimoto, C. 1999. Enhancement of phagocylic and chemokinetic activities of rainbow trout head kidney cells by C-reactive protein. Am. J Vet. Res ., 60, 240

 

3 ) Lee, SI., Ohashi, K., Morimura, T., Sugimoto, C., and Onuma, M. 1999. Reisolation of Marek's disease virus from T cell subsets of vaccinated and non-vaccinated chickens. Arch. Virol ., 144, 45 -54.

 

4 ) Kawazu, S., Kamio, T., Kakuda, T., Terada, Y., Sugimoto, C., and Fujisaki, K. 1999. Phylogenetic relationships of the benign Theileria species in cattle and Asian buffalo based on the major piroplasm surface protein (p33/34) gene sequences. Int. J Parasitol ., 29, 613-618.

 

5 ) Mulenga, A., Sugimoto, C., Sako, Y., Ohashi, K., Musoke, A., Shubash, M., and Onuma, M. 1999. Molecular characterization of a Haemaphysalis longicornis tick salivary gland-associated 29-kilodalton protein and its effect as a vaccine against tick infestation in rabbits. Infect. Immun., 67, 1652-1658.

 

6 ) Ochiai, K., Ohashi, K., Mukai, T., Kimura, T., Umemura, T., and Itakura, C. 1999. Evidence of neoplastic nature and viral aetiology of so-called fowl glioma. Vet. Rec ., 145, 79-81.

 

7 ) Kabeya, H., Ohashi, K., Sugimoto, C., and Onuma, M. 1999. Bovine leukaemia virus envelope peptides cause immuno-modulation in BALB/C mice. Vet. Immunol. Immunopathol ., 68, 39-48.

 

8 ) Sako, Y., Sugimoto, C., and Onuma, M. 1999. Cloning of a cysteine proteinase gene of Theileria sergenti . J. Vet. Med. Sci ., 61, 271-273.

 

9 ) Sako, Y., Sugimoto, C., and Onuma, M. 1999. Expression of a major piroplasm surface protein of Theileria sergenti in sporozoite stage. J Vet. Med. Sci., 61, 275-277.

 

10) Kabeya, H., Ohashi, K., Sugimoto, C., and Onuma, M. 1999. Characterization of immune responses caused by bovine leukemia virus envelope peptides in sheep. J Vet. Med. Sci., 61, 475-480.

 

11) Mulenga, A., Sugimoto, C., Ingram, G., Ohashi, K., and Onuma, M. 1999. Molecular cloning of two Haemaphysalis longicornis cathepsin L-like cysteine proteinase genes. J Vet. Med. Sci ., 61, 497-502 .

 

12) Cho, KO., Meas, S., Park, NY., Kim, YH., Lim, YK., Endoh, D., Lee, SI., Ohashi, K., Sugimoto, C., and Onuma, M. 1999. Seroprevalence of bovine immunodeficiency virus in dairy and beef cattle herds in Korea. J Vet. Med. Sci., 61, 549-551.

 

13) Mulenga, A., Sugimoto, C., and Onuma, M. 1999. Characterization of proteolylic enzymes expressed in the midgut of Haemaphysalis longicornis. Jpn. J Vet. Res ., 46, 179-184.

 

14) Cho, KO., Ohashi, K., and Onuma, M. 1999. Electron microscopic and immunohisto-chemical localization of Marek's disease (MD) herpesvirus particles in MD skin lymphomas. Vet. Pathol ., 36, 314-320.

 

15) Sako, Y.,Asada, M., Kubota, S., Sugimoto, C., and Onuma, M. 1999. Molecular cloning and characterisation of 23-kDa piroplasm surface proteins of Theileria sergenti and Theileria buffeli. Int. J Parasitol ., 29, 593-599.

 

16) Kabeya, H., Ohashi, K., Oyunbileg, N., Nagaoka, Y., Aida, Y., Sugimoto, C., Yokomizo, Y., and Onuma, M. 1999. Up-regulation of tumor necrosis factor alpha mRNA is associated with bovine-leukemia virus (BLV) elimination in the early phase of infection. Vet. Immunol. Immunopathol ., 68, 255-265.

 

17) Takashima, Y., Xuan, X., Matsumoto, Y., Onuma, M., and Otsuka, H. 1999. Antibodies produced by mice immunized with recombinant vaccinia viruses expressing two different types of a major Theileria sergenti surface antigen (p32) react with the native surface antigen. Vet. Parasitol ., 84, 65-73.

 

18) Sarataphan, N., Nilwarangkoon, S., Tananyutthawongese, C., Kakuda, T., Onuma, M., and Chansiri, K. 1999. Ge-netic diversity of maj or piroplasm surface protein genes and their allelic variants of Theileria parasites in Thai cattle. J Vet. Med. Sci ., 61, 991-994.

 

19) Morimura, T., Cho, KO., Kudo, Y., Hiramoto, Y., Ohashi, K., Hattori, M., Sugimoto, C., and Onuma, M. 1999. Anti-viral and anti-tumor effects induced by an attenuated Marek's disease virus in CD 4 -or CD 8 -deficient chickens. Arch. Virol ., 144, 1809-1818.

 

20) Ohashi, K., Morimura, T., Takagi, M., Lee, SI., Cho, KO., Takahashi, H., Maeda, Y., Sugimoto, C., and Onuma, M. 1999. Expression of bcl- 2 and bcl-x genes in lym-phocyles and tumor cell lines derived from MDV-infected chickens. Acta Virol ., 43, 128-132.

 

21) Cho, KO., Endoh, D., Onuma, M., and Itakura, C. 1999. Analysis of transcriptional and translational activities of Marek's disease (MD) virus genes in MD central nervous system lesions in chickens. Avian Pathol ., 28, 47-53.

 

22) Kim, GH., Lee, KK., and Onuma, M. 1999. Susceptibility of Theileria sergenti infection in holstein cattle compared to Korean native cattle on Cheju island. J Protozool. Res., 9., 103-112.

 

Publications other than original articles

 

1 ) Sugimoto, C. 1999. Anaplasma infections. In : Color atlas of infectious diseases, pp. 400, Mikami, T. and Maruyama, T. eds., Buneido Syuppan, Tokyo (in Japanese) .

 

2 ) Sugimoto, C. 1999. Trypanosoma infections. In : Color atlas of infectious diseases, pp447-449, Mikami, T. and Maruyama, T. eds., Buneido Syuppan, Tokyo (in Japanese) .

 

3 ) Takahashi, T., and Onuma, M. 1999. Infectious diseases of fish and its immunity against these diseases. J Vet. Med ., 52, 467-470 (in Japanese).

 

4 ) Onuma, M., Mulenga, A., Nakajima, M., and Sugimoto, C. 1999. Development of anti-tick vaccine. Douyakukenkyu , 59, 1 1-23 (in Japanese) .

 

5 ) Rakha, N. K., Sugimoto, C., and Onuma, M. 1999. Recent developments in diagnosis and prophylaxis of Theileria annulata and T sergenti infection . Cur. Trends Immunol ., 2, 135-143.

 

6 ) Kabeya, H., and Onuma, M. 1999. Pathogenesis and cyiokine profiles of bovine leukemia virus infected animals. Bull. Jap. Soc. Vet. Path., Sep. 5, 6 - 9 (in Japanese) .

 

7 ) Onuma, M. 1999. Bovine retroviruses. In : New Veterinary Diagnosis Handbook. pp274-277, Hasegawa, A. ed. Inters, Tokyo (in Japanese) .

 

8 ) Onuma, M., Kitamura, N., Noguchi, T., Watanabe, T., Enoto, T., Hasebe, K., and Abe, K. 1999. Schooling in the graduate school; a study on the common curricula for graduate schools in Hokhaido University (a research report in 1998-1999 fiscal year) . J Higher Educ. Lifelong Learn ., 6, 139-155. (in Japanese).

 

9 ) Onuma, M. 1999. Bovine viral diarrhea-mucosal disease. In : Veterinary infectious diseases, pp92-94, Shimizu, Y., Kanoe, M., Tabuchi, K., Hiramune, T., and Mikami, T. eds., 5 th ed. Klndai Syuppan, Tokyo (in Japanese) .

 

10) Onuma, M. 1999. Bovine mammillitis. ibid , pp 94 (in Japanese).

 

11) Onuma, M. 1999. Bovine rhinovirus infection. ibid , pp1OO (in Japanese) .

 

12) Onuma, M. 1999. Bovine enterovirus infection. ibid , pp1O1 (in Japanese) .

 

13) Onuma, M. 1999. Jembrana Disease. ibid , pp104 (in Japanese).

 

14) Onuma, M. 1999. Trypanosomiasis in cattle. ibid , pp153-154 (in Japanese) .

 

15) Onuma, M. 1999. Wesselsbron disease. ibid , pp161 (in Japanese) .

 

16) Onuma, M. 1999. Border disease. ibid , pp162 (in Japanese) .

 

17) Sugimoto, C. 1999. Anaplasmosis. ibid , pp135-136 (in Japanese) .

 

18) Sugimoto, C. 1999. Bovine eperylhrozoonosis. ibid , pp136 (in Japanese) .

 

19) Sugimoto, C. 1999. Bovine babesiosis. ibid , pp149-150 (in Japanese).

 

20) Sugimoto, C. 1999. Trichomoniasis in cattle. ibid , pp152-153 (in Japanese) .

 

21) Sugimoto, C. 1999. Contagious equine metritis. ibid , pp187 (in Japanese) .

 

22) Sugimoto, C. 1999. Strangles. ibid , pp188 (in Japanese) .

 

23) Sugimoto, C. 1999. Eperythrozoonosis in swine. ibid , pp231 (in Japanese).

 

1998

Original articles

 

1 ) Murata, M., Sugimoto, C., Kodama, H., and Onuma, M. 1998. A two-dimensional electrophoretic analysis of serum proteins of rainbow trout (Oncorhynchus mykiss) treated with inflammation inducers. Bull. Osaka Pref. Univ. Series B. 50: 59-65.

 

2 ) Tasaki, T., Nakamura, A., Itoh, S., Ohashi, K., Yamamoto, Y., Masuda, M., Iwata, H., Kazusaka, A., Kamataki, T., and Fujita, S. 1998. Expression and characterization of dog CYP2D15 using baculovirus expression system. J. Biochem. 123:162-168.

 

3 ) Wang, C-T., Kubota, S., Kakuda, T., Kuo, C-C., Hsu, T-L., and Onuma, M. 1998. Survey of Theileria parasite infection in cattle in Taiwan. J. Vet. Med. Sci., 60: 253-255.

 

4 ) Kakuda, T., Kubota, S., Sugimoto, C., Baek, B., Yin. H., and Onuma, M. 1998. Analysis of imminodominant piroplasm surface protein genes of benign Theileria parasites distributed in China, Korea by allele-specific polymerase chain reaction. J. Vet. Med. Sci., 60, 237-239.

 

5 ) Sakakibara, N., Kabeya, H., Ohashi, K., Sugimoto, C., and Onuma, M. 1998. Epitope mapping of bovine leukemia virus transactivator ptotein Tax. J. Vet. Med. Sci., 60, 599-605.

 

6 ) Hanafusa, Y., Sudo, T., Sako, Y., Kanemaru, T., Kamada, M., Zweygarth, E., Sugimoto, C., and Onuma, M. 1998. Identification of B cell epitopes of a 30 kDa Babesia equi merozoite surface protein. J. Vet. Med. Sci., 60:563-567.

 

7 ) Iwasaki, T., Kakuda, T., Sako, Y., Sugimoto, C., and Onuma, M. 1998. Differentiation and quantification of Theileria sergenti piroplasm types using type-specific monoclonal antibodies. J. Vet. Med. Sci., 60:665-669.

 

8 ) Savini, G., Onuma, M., Scaramozzino, P., Kakuda, T., Semproni, G., and Langella, V. 1998. First report of Theileria sergenti and T. buffeli/orientalis in cattle in Italy. Ann. New York Acad. Sci. 849: 404-407.

 

9 ) Kim, S-J., Tsuji, M., Kubota, S., Wei, Q., Lee, J-M., Ishihara, C., and Onuma, M. 1998. Sequence analysis of the major piroplasm surface protein gene of benign bovine Theileria parasites in East Asia. Int. J. Parasitol., 28:1219-1227.

 

10) Kakuda, T., Shiki, M., Kubota, S., Sugimoto, C., Brown, W. C., Kosum, C., Nopporn, S., and Onuma, M. 1998. Phylogeny of benign Theileria species from cattle in Thailand, China and the USA based on the major piroplasm surface protein and small subunit of ribosomal RNA genes. Int. J. Parasitol., 28:1261-1267.

 

11) Cho, K-O., Park, N-Y., Endoh, D., Ohashi, K., Sugimoto, C., Itakura, C., and Onuma, M. 1998. Cytology of feather pulp lesions from Marek's disease (MD) virus-Infected chickens and its application for diagnosis and prediction of MD. J. Vet. Med. Sci. 60: 843-847.

 

12) Takagi, M., Ohashi, K., Morimura, M., Sugimoto, C. and Onuma, M. 1998. Analysis of tumor suppressor gene p53 in chicken lymphoblastoid tumor cell lines and field tumors. J. Vet. Med. Sci. 60: 923-929.

 

13) Hanafusa, Y., Cho, K-O., Kanemaru, T., Wada, R., Sugimoto, C., and Onuma, M. 1998. Pathogenesis of Babesia caballi infection in experimental horses. J. Vet. Med. Sci. 60: 1127-1132.

 

14) Meas, S., Kabeya, H., Yoshihara, S., Ohashi, K., Matsuki, S., Mikami, Y., Sugimoto, C., and Onuma, M. 1998. Seroprevalence and field isolation of bovine immunodeficiency virus. J. Vet. Med. Sci. 60: 1195-1202.

 

15) Cho, K-O., Park, N-Y., Park, I-C., Kang, B-K., and Onuma, M. 1998. Metastatic intracavitary cardiac aortic body tumor in a dog. J. Vet. Med. Sci. 60: 1251-1253.

 

16) Cho, K-O., Endoh, D., Qian, J-F., Ochiai, K., Onuma, M., and Itakura, C. 1998. Central nervous system lesions induced experimentally by a very virulent strain of Marek’s disease virus in Marek’s disease-resistant chickens. Avian Pathol. 27: 512-517.

 

17) Tana, Watarai, S., Onuma, M., Aida, Y., Kagitani, H., Kodama, H., and Yasuda, T. 1998. Antitumor effect of diphtheria toxin A-chain gene-containing cationic liposomes conjugated with monoclonal antibody directed to tumor-associated antigen of bovine leukemia cells. Jpn. J. Cancer Res. 89: 1202-1211.

 

Publications other than original articles

 

1 ) Morimura, T., Ohashi, K., Sugimoto, C., and Onuma, M. 1998. Pathogenesis of Marek’s disease (MD) and possible mechanisms of immunity induced by MD vaccine. J. Vet. Med. Sci. 60:1-8.

 

2 ) Ohashi K. 1998. Anti-tumor vaccines. J. Vet. Med. 51: 593-598. (in Japanese).

 

3 ) Onuma, M., Kakuda, T., and Sugimoto, C. 1998. Theileria parasite infection in East Asia and control of the disease. Com. Immunol. Microbiol. Infect. Dis. 21: 165-177.

 

4 ) Onuma, M. 1998. Immunology of calf. Doyakukenkyuu. 57:22-33. (in Japanese).

 

5 ) Noguchi, T., Kitamura, N., Watanabe, T., Onuma, M., Haebe, K., Enoto, T., and Abe, K. 1998. On the curricula in Graduate Schools in Hokkaido University: a report in 1997-1998 fiscal year. J. Higher Educ. Life. Learn. 4: 95-110. (in Japanese).

 

1997

Original articles

 

1 ) Nambota, A. M., Lovelace, C. E., Chitambo, H., Kakuda, T., Sugimoto, C. and Onuma, M. Characterization of some Theileria parva stocks from Zambia using monoclonal antibodies. J. Vet. Med. Sci., 59:1-4.

 

2 ) Lee, J. T., Watarai, S., Kakidani, H., Onuma, M., Zhao, D. D. and Yasuda, T. 1997. Evaluation of cationic liposomes for delivery of diphtheria toxin A-chain gene to cells infected with bovine leukemia virus. J. Vet. Med. Sci., 59:169-174.

 

3 ) Tana, Watarai, S., Lee, J. T., Onuma, M., Ochiai, K., Kakidani, H. and Yasuda, T. 1997. In vivo antitumor effect of cationic liposomes containing diphtheria toxin A-chain gene on cells infected with bovine leukemia virus. J. Vet. Med. Sci., 59:617-619.

 

4 ) Morimura, T., Ohashi, K., Kon, Y., Hattori, M., Sugimoto, C. and Onuma, M. 1997. Apoptosis in peripheral CD4+ T cells and thymocytes by Marek's disease virus-infection. Leukemia., 11 Suppl 3:206-208.

 

5 ) Ohishi, K., Kabeya, H., Amanuma, H. and Onuma, M. 1997. Peptide-based bovine leukemia virus (BLV) vaccine that induces BLV-Env specific Th-1 type immunity. Leukemia., 11 Suppl 3:223-226.

 

6 ) Okada, K., Tanaka, Y., Murakami, K., Chiba, S., Morimura, T., Hattori, M., Goryo, M. and Onuma, M. 1997. Phenotype analysis of lymphoid cells in Marek’s disease of CD4+ or CD8+ T-cell-deficient chickens - occurrence of double negative T-cell tumor. Avian Pathol., 26:525-534.

 

7 ) Samui, K. L., Inoue, S., Mweene, A. S., Nambota, A. M., Mlangwa, J. E. D., Chiloications

 

Publications other than original articles

 

1 ) Ohashi, K., Morimura, T., Takagi, M., Sugimoto, C. and Onuma, M. 1997. Transformation and apoptosis induced by Marek’s disease virus. Biosci. Biotechnol., 35: 748-750. (in Japanese).

 

2 ) Onuma, M., Morimura, T., Lee, S. I. and Ohashi, K. 1997. Immunosuppression caused by Marek’s disease (MD) virus and the protection mechanism of MD vaccines (1). Doyakukenkyu, 55: 33-41. (in Japanese).

 

3 ) Onuma, M., Morimura, T., Lee, S. I. and Ohashi, K. 1997. Immunosuppression caused by Marek’s disease (MD) virus and the protection mechanism of MD vaccines (2). Doyakukenkyu, 56: 25-30. (in Japanese).

 

1996

Original papers

 

1 ) Kabeya, H., Ohashi, K., Ohishi, K., Sugimoto, C., Amanuma, H. and Onuma, M. 1996. An effective peptide vaccine to eliminate bovine leukemia virus (BLV) infected cells in carrier sheep. Vaccine, 14: 1118-1122.

 

2 ) Ohishi, K., Kabeya, H., Amanuma, H. and Onuma, M. 1996. Induction of bovine leukemia virus env-specific Th-1 type immunity in mice by vaccination with short synthesized peptide-liposome. Vaccine, 14: 1143-1148.

 

3 ) Kubota, S., Sugimoto, C., Kakuda, T. and Onuma, M. 1996. Analysis of immunodominant piroplasm surface antigen alleles in mixed populations of Theileria sergenti and T. buffeli. Int. J. Parasitol., 26: 741-747.

 

4 ) Nambota, A. M., Lovelace, C. E. A., Chitambo, H., Kakuda, T., Sugimoto, C. and Onuma, M. 1997. Characterization of some Theilena parva stocks from Zambia using monoclonal antibodies. J. Vet. Med. Sci. , 59: 1-4.

 

5 ) Morimura, T., Ohashi, K., Kon, Y., Hattori, M., Sugimoto, C. and Onuma, M. 1996. Apoptosis and CD8-down-regulation in the thymus of chickens infected with Marek's disease virus. Arch. Virol., 141: 2243-2249.

 

6 ) Hirai, N., Kabeya, H., Ohashi, K., Sugimoto, C. and Onuma, M. 1996. Detection of antibodies against bovine immunodeficiency-like virus in daily cattle in Hokkaido. J. Vet. Med Sci., 58: 455-457.

 

7 ) Samui, K. L., Nambota, A. M., Mweene, A. S. and Onuma, M. 1996. African swine fever in Zambia: potential financial and production consequences for the commercial sector. Jpn. J. Vet. Res. 44: 119-124.

 

8 ) Yamamoto, H., Hattori, M., Ohashi, K., Sugimoto, C. and Onuma, M. 1996. Characterization of extrathymic T cells of chickens. Vet. Immunol. Immunopathol. 49: 375-386.

 

9 ) Hirai, N., Kabeya, H., Ohashi, K., Sugimoto, C. and Onuma, M. 1996. Immunomodulative effects of bovine immunodefficiency-like virus (BIV)-infection and mixed infection of BIV and bovine leukemia virus on sheep. Jpn. J. Vet. Res. 44: 153-163.

 

10) Watarai, S., Sugimoto, C., Hosotani-Kaihara, K., Kobayashi, K., Onuma, M., Lee, J-T., Kushi, Y., Handa, S. and Yasuda, T. 1996. Isolation and characterization of gangliosides from Theileria sergenti. J. Vet. Med Sci., 58: 1099-1105.

 

11) Kubota, S., Sugimoto, C. and Onuma, M. 1996. Population dynamics of Theileria sergenti in persistently infected cattle and vector ticks analysed by a polymerase chain reaction. Parasitology, 112: 437 442.

 

12) Renshaw, R. W., Soine, C., Weinkle, T., O'Connell, P. H., Ohashi, K., Watson, S., Lucio, B., Harrington, S. and Schat, K. A. 1996. A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. J. Virol. 70: 8872-8878.

 

13)Hiramoto, Y., Lee, S. 1., Morimura, T., Ohashi, K., Sugimoto, C. and Onuma, M. 1996. Re-isolation of Marek's disease virus from T cell subsets of vaccinated and non-vaccinated chickens. In: Current Research on Mareks Disease, pp. 130-135, Silva, R. F., Cheng, H. H., Coussens, P. M., Lee, L. F. and Velicer, L. F. eds., American Association of Avian Pathologists, Kennett Square, PA.

 

14) Takagi, M., Ohashi, K., Morimura, T., Sugimoto, C. and Onuma, M. 1996. Analysis of the chicken p53 in chicken Iymphoblastoid cell lines and field tumors. ibid, pp. 251-256.

 

15) Morimura, T., Ohashi, K., Hattori, M., Sugimoto, C. and Onuma, M. 1996. Apoptosis of CD4+ T cell in vivo and non-responsiveness of CD4+ and CD8+ T cells in vitro observed in chickens infected with Marek's disease virus. ibid, pp. 335-340.

 

Publications other than original articles

 

1 ) Onuma, M. 1996. Bovine spongiform encephalopathy and its relationship to human diseases. J. Hokkaido Vet. Med. Assoc., 40: 117-121 (in Japanese).

 

2 ) Onuma, M. 1996. Change of outbreak of infectious diseases and those control. J. Vet. Med Sci., 58: J35-40 (in Japanese).

 

3 ) Ito, T. and Onuma, M. 1996. Current research on bovine cytokines. J. Vet. Med., 50: 160-164 (in Japanese).

 

4 ) Monmura, T., Ohashi, K., Hattori, M., Sugimoto, C. and Onuma, M. 1996. Apoptosis induced by Marek's disease virus. Report for Jpn. Vet. Pathol. Soc., 8-11 (in Japanese).

 

5 ) Onuma, M. 1996. Workshop summary: Haemospordia. Vet. Parasitol. , 64: 167-169.

 

6 ) Kabeya, H., Ohishi, K., Kakuda, T. and Onuma, M. 1996. Vaccine development and cytokine transcriptional profiles in ruminants infected with intracellular pathogens. J. Interferon & Cytokine Res., 16: 669 (Suppl. ).

 

7 ) Okada, K., Sonoda, K., Koyama, M., Goryo, M., Kabeya, H., Onuma, M., Ohishi, K. and Amanuma, H. 1996. Delayed-type hypersensitivity responses against BLV in sheep vaccinated with synthesized peptide of BLV envelope glycoprotein. ibid, 16 (suppl.): 671.

 

8 ) Onuma, M., Kubota, S., Kakuda, T. and Sugimoto, C. 1996. Diagnosis and typing of theileria parasite allele-specific PCR. In: Proc. VIIIth Int. Symp. Vet. Lab. Diagnos., Jerusalem, pp. 37.

 

9 ) Sugimoto, C. 1996. Economic importance of theileriosis in Japan. In: Proc. Int. Symp. Tick-borne Dis., Xian, China, pp. 13.

 

10) Zhang, W. Z., Sugimoto, C. and Onuma, M. 1996. Antigenic and genetic characterization of Theiiena sergenti. ibid, pp. 20.

 

11) Tsuji, M., Kim, S. J., Kubota, S. and Onuma, M. 1996. Comparative sequence analysis on the major piroplasm surface protein gene of bovine benign theileria parasites distributed in east Asia. ibid, pp. 24.

 

12) Onuma, M., Kubota, S., Kakuda, T., Sako Y., Asada, M., Kabeya, H. and Sugimoto, C. 1996. Control of theileria infection by vaccination. ibid, pp. 34.

 

13) Sugimoto, C., Sudo, T., Hanafusa, Y., Iwasaki, T., Onuma, M., Kanemaru, T. and Kamada, H. 1996. Molecular characterization of a 30kDa Babesia equi merozoite surface antigen. ibid, pp. 49.

 

14) Onuma, M. 1996. Infection and immunity. In: Immunology of Animals, pp. 140-150, Onuma, M., Onodera, T. and Yamanouchi, K. eds., Buneidou Shuppan, Tokyo (in Japanese).

 

15) Onuma, M. 1996. Immunity to tumors. ibid, pp. 151-154 (in Japanese).

 

16) Ali, S., Sugimoto, C. and Onuma, M. 1996. Equine piroplasmosis. J. Equine Sci., 7: 67-77.