＜ 生理学教室 ＞
2007
Original articles
１）Gautam, S. H., Otsuguro, K., Ito, S., Saito, T. and Habara, Y. 2007.
T-type Ca2+ channels contribute to IBMX/forskolin- and K+- induced Ca2+ transients in porcine olfactory receptor neurons. Neurosci. Res., 57: 129-139
２）Gautam, S. H., Otsuguro, K., Ito, S., Saito, T. and Habara, Y. 2007. T-type Ca2+ channels mediate propagation of odour-induced Ca2+ transients in rat olfactory receptor neurons. Neuroscience, 144: 702-713
３）Sankar, R., Archunan, G. and Habara, Y. 2007. Detection of oestrous-related
odour in bovine (Bos taurus) saliva: bioassay of identified compounds.
Animal, 1: 1321-1327
2006
Original articles
１）Gautam, S. H., Otsuguro, K., Ito, S., Saito, T. and Habara, Y.２００６．Intensity of odorant stimulation affects mode of Ca２＋ dynamics in rat olfactory receptor neurons. Neurosci. Res.,５５：４１０‐４２０．
２）Kuroda, T, Satoh, Y., Akutsu-Yamaguchi, H., Shikanai, Y., Miyata, S., Saino, T., Russa, D., Habara, Y. and Cui, Z. J.２００６． Quantitative analysis of photodamage during fluorescence bioimaging : monitoring of nitric oxide production using DAF‐２．Bioimages,１４：９‐１８．
2005
Original articles
１）Otsuguro, K. , Gautam, S. H., Ito, S., Habara, Y. and Saito, T．２００５．Characterization of forskolin-induced Ca２＋signals in rat olfactory receptor neurons. J. Pharmacol. Sci.,９７：５１０‐５１８
２）Sato, K., Ponganis, P. J., Habara, Y. and Naito, Y．２００５．Emperor penguins adjust swim speed according to the above-water height of ice holes through which they exit. J. Exp. Biol.,２０８：２５４９‐２５５４
３）Yamaguchi , S. and Ishikawa , T ．２００５． Electrophysiological characterization of native Na＋ -HCO３－cotransporter current in bovine parotid acinar cells. J. Physiol.，５６８（Pt１）：１８１‐１９７
2004
Original articles
1 ) Iwanaga, H. and Habara, Y. 2004. Oscillatory calcium responses mediated by P2Y2 purinergic receptors in terminal schwann cells of longitudinal lanceolate ending isolated from rat vibrissae. J. Comp. Neurol., 475: 416-425.
2 ) Hayashi, M., Kunii, C., Takahata, T. and Ishikawa, T. 2004. ATP-dependent regulation of SK4/IK1-like currents in rat submandibular acinar cells: possible role of cAMP-dependent protein kinase. Am. J. Physiol. Cell Physiol., 286(3):C635-46.
3 ) Inagaki, A., Yamaguchi, S., and Ishikawa, T. 2004. Amiloride-sensitive epithelial Na+ channel currents in surface cells of rat rectal colon. Am. J. Physiol. Cell Physiol., 286(2):C380-90.
Publications other than original articles
1 ) Gautum, S. H., Otsuguro, K., Ito, S., Saito, T. and Habara, Y. 2004. Spatiotemporal dynamics of cytosolic Ca2+ in isolated pig olfactory receptor neurons.138th Congress of Japanese Society of Veterinary Science. September, Sapporo.
2003
Original articles
1 ) Cui, Z. J., Zhou, Y. D., Satoh, Y. and Habara, Y. 2003. A physiological role for protoporphyrin IX photodynamic action in the rat Harderian gland. Acta Physiol. Scand ., 179: 149-154.
2 ) Ishikawa, T., Jiang, C., Stutts, M. J., Marunaka, Y. and Rotin, D. 2003. Regulation of the epithelial Na+ channel by cytosolic ATP. J. Biol. Chem., 278: 38276-38286.
3 ) Hayashi, M., Komazaki, S. and Ishikawa, T. 2003. An inwardly rectifying K+ current in bovine parotid acinar cells: possible involvement of Kir2. 1. J. Physiol., 547. 1: 255-269.
4 ) Takahata, T., Hayashi, M. and Ishikawa, T. 2003. SK4/IK1-like channels mediate TEA-insensitive, Ca2+-activated K+ currents in bovine parotid acinar cells. Am. J. Physiol. Cell. Physiol., 284: C127-C144.
5 ) Komagiri, Y., Kitamura, N. 2003. Effect of intracellular dialysis of ATP on the hyperpolarization-activated cation current in rat dorsal root ganglion neurons. J. Neurophysiol., 90: 2115-2122.
Publications other than original articles
1 ) Habara, Y. Animal Physiology. Kanno, T. and Taya, K. eds. 2003. Asakura shoten
2 ) Takahashi-Iwanaga, H. and Habara, Y. 2003. Extracellulary-applied ATP evokes multifocal calcium oscillations in Schwann sheaths enveloping lanceolate sensory endings. Society for ATP-adenosine
3 ) Otsuguro, K., Gautam, S. H., Ito, S., Habara, Y. and Saito, T. 2003. Intracellular Ca2+ signaling via cAMP in rat olfactory neuronal cells. 17th Hokkaido meeting for drug action
4 ) Otsuguro, K., Gautam, S. H., Ito, S., Habara, Y. and Saito, T. 2003. Intracellular Ca2+ signaling by forskolin in rat olfactory neuronal cells. 138th Meeting for Society for Veterinary Medical Sciences
5) Gautam, S. H., Otsuguro, K., Ito, S., Saito, T. and Habara, Y. 2003. Spatiotemporal dynamics of Ca2+ in rat olfactory receptor neurons. 138th Meeting for Society for Veterinary Medical Sciences
2002
Original articles
1 ) Takahashi-Iwanaga, H. and Habara, Y. 2002. Adenosine 5’-triphosphate-evoked calcium responses in terminal Schwann cells of lanceolate sensory endings isolated from rat vibrissae. Neurosci. Lett. 324: 137-140.
2 ) Fukushima, N., Ishii, I., Habara, Y. and Chun, J. 2002. Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines; actin depolymerization by Ca2+-α-actin and polymerization by RHO. Molecular Biology of the Cell . 13: 2692-2705.
3 ) Hanwell, D., Ishikawa, T., Saleki R. and Rotin, D. 2002. Trafficking and Cell Surface Stability of the Epithelial Na+ Channel Expressed in Epithelial Madin-Darby Canine Kidney Cells. The Journal of Biol. Chem., 277(12) : 9772-9779.
Publications other than original articles
1 ) Takahashi-Iwanaga, H. and Habara, Y. 2002. ATP-evoked Ca2+ wave in lanceolate sensory endings. NIPS Meeting 2002 “Elucidation of Physiological Function of ATP Receptors”.
2 ) Takahashi-Iwanaga, H. and Habara, Y. 2002. Analysis of Ca2+ response to extracellular ATP in Schawnn cells of islated lanceolate sensory endings by image analysis using confocal microscopy. Annual Meeting of Hokaido-Tohoku Anatomical Society.
2001
Original articles
1 ) Hashikura, S., Satoh, Y., Cui, Z. J. and Habara, Y. 2001. Photodynamic action inhibits compound 48/80-induced exocytosis in rat peritoneal mast cells. Jpn. J. Vet. Res., 49: 239-247.
Publications other than original articles
1 ) Habara, Y. 2001. Pathophysiology of polydipsia and polyuria. SA Medicine, 3: 3-9.
2 ) Takahashi-Iwanaga, H. and Habara, Y. 2001. Isolation of lanceolate sensory endings form rat vibrissae ? preserved morphology and responses to ATP in Schwann cells of endings. Annual Meeting of Hokkaido Physiological Society
3 ) Takahashi-Iwanaga, H., Abe, A. and Habara, Y. 2001. Image analysis of intracellular calcium signaling in Schwann cell of isolated lanceolate sensory endings. Annual Meeting of Hokaido-Tohoku Anatomical Society.
4 ) Takahashi- Iwanaga, H. and Habara, Y. 2001. Specific morphology and responses to ATP in lanceolate sensory endings. NIPS Meeting 2001 “Glia and Brain Function”.
2000
Original articles
1 ) Ishihara, Y., Sakurai, T., Habara, Y., Busik, J. V., Kanno, T. and Terakawa, S. 2000. Exocytosis in the dissociated pancreatic acinar cells of the guinea pig directly visualized by VEC-DIC microscopy. Biochem. Biophys. Res. Commum. 277: 134-137.
2 ) Cui, Z. J., Habara, Y., and Satoh, Y. 2000. Photodynamic modulation of adrenergic stimulated increases in intracellular calcium in the isolated rat hepatocytes. Biochem. Biophys. Res. Commum. 277: 705－710.
3 ) Takahashi-Iwanaga, H., Kim, M. J., Abe, K. and Hbara, Y. 2000. Oscillatory Ca2+ signals evoked by cholinergic stimulation in isolated rat pancreatic duct cells. Biomedical Res. 21: 283-290.
Publications other than original articles
1 ) Sato, H., Saito, M., Hosoya, R., Habara, Y. and Kawahara, K. 2000. Spatially restricted acute neuronal death induced by disruption of calcium homeostasis using caged ionophore. 77th Annual Meeting of Japanese Physiological Society.
2 ) Staub, O., Abriell, H., Plant, P., Ishikawa, T., Kanelis, V., Salleki, R., Horisberger. J-D, Schild, L., and Rotin, D. 2000. Regulation of ENaC by Nedd 4 and Ubiquitination. Kidney International 57: 809-815.
3 ) Komagiri, Y., Kitamura, N., 2000. Studies about intracellular modulating factors of hyperpolarization-activated cation current in rat dorsal root ganglion neurons. 129ｔｈ Conference of Japanese Society of Veterinary Science , abstract p166(in Japanese)
1999
Original articles
1 ) Yoshihashi, K. and Habara, Y. 1999. Contribution of Na+/Ca2+ exchanger to glucose-induced [Ca2+]i increase in rat pancreatic islet. Jpn. J. Physiol. 49, 71-80.
2 ) Sweiry, J. H., Shibuya, I.,Asada, N., Niwa, K. , Doolabh, K. , Habara, Y. , Kanno, T. and Mann, G. E. 1999. Acute oxidative stress modulates secretion and repetitive Ca2+ spiking in rat exocrine pancreas. Biochem. Biophys. Acta 1454, 19-30.
3 ) Suzuki, S.,Habara,Y. and Kanno, T. 1999. Effect of substance P on nicotine-induced intracellular Ca2+ dynamics in bovine adrenal chromaffin cells. Jpn. J. Vet. Res. 47, 3 -12.
4 ) Satoh, Y., Williams, M. R. and Habara, Y. 1999. Effects of AIF 4 -and ATP on intra-cellular calcium dynamics of crypt epithelial cells in mouse small intestine. Cell Tissue Res. 298, 295-305.
5 ) Kasai, Y., Ito, S., Kitamura, N., Ohta, T. and Nakazato, Y. 1999. Online measurement of adenosine triphosphate and catecholamine released from adrenal chromaffin cells. Comparative Biochemistry and Physiology Part A 122 : 363-368.
Publications other than original articles
1 ) Sato, H., Saito, M., Habara, Y. and Kawahara, K. 1999. Acute neuronal death caused by the disruption of intracellular calcium homeostasis in neuron-glia-mixed-culture. BPES '99 73-76.
2 ) Sato, H., Saito, M., Hosoya, R., Kawahara, K. and Habara, Y. 1999. Photon-induce neuronal death in caged compound-loaded neuron-glia-mixed-culture. 79th Hokkaido Medical Congress, abstract pl8.
3 ) Tabuchi, M., Yayou, K., Hayashi, M., Sekiguchi, M., Inagaki, A., Takeshita, K. and Habara,Y. 1999. Specific metabolism in the brain ofthe ruminants. 128th Conference of Japanese Society of Veterinary Science, abstract p267.
4 ) Staub, O., Plant, P., Ishikawa T., Schild, L. and Rotin D. 1999. Regulation of ENaC by interacting proteins and by ubiquitination. Current Topics in Membranes 47, 65-85.
1998
Original articles
1 ) Hori, J., Sato, H., Furubayashi, Y., Nagashima, K., Habara, Y. and Kawahara, K. 1998. Glutamate-induced neurotoxicity in neuron-astrocyte co-cultures from the embryonic rat cortex. Technical Report of IEICE 3: 79-84
2 ) Oomori, Y., Habara, Y. and Kanno, T. 1998. Muscarinic and nicotinic receptor-mediated Ca2+ dynamics in rat adrenal chromaffin cells during development. Cell. Tissue. Res. 294: 109-123
3 ) Sato, H., Hori, J., Habara, Y. and Kawahara, K. 1998. Long-lasting intracellular calcium elevation causes nuronal death in neuron-astrocyte co-cultures. Technical Report of IEICE 6: 7-12
4 ) Hayashi, M. and Kanno, T. 1998. Photodynamic stimulation causes sustained increase in intracellular calcium concentration in cells of small cell lung carcinoma. Jpn. J. Vet. Res. 46: 65-72
5 ) Ishikawa, T., Marunaka, Y. and Rotin, D. 1998. Electrophysiological characterization of the rat epithelial Na+ channel (rENaC) expressed in MDCK cells : Effects of Na+ and Ca2+. J. Gen. Physiol. 111:825-846
6 ) Kitamura , N., Ohta , T., Ito, S. and Nakazato, Y. 1998. Calcium channel current facilitation in porcine adrenal chromaffin cells. Pflüger. Archiv-Eur. J. Physiol. 435: 781-788
7 ) Sugawara, T., Kitamura, N., Ohta, T., Ito, S. and Nakazato, Y. 1998. Inhibitory effects of tacrine and physostigmine on catecholamine secretion and membrane currents in guinea-pig adrenal chromaffin cells. Fundamental and Clinical Pharmacology 12: 279-285
Publications other than original articles
1 ) Yoshihashi, K. and Habara, Y. 1998. Contribution of Na+/Ca2+ exchanger to glucose-induced increase in intracellular Ca2+ concentration in rat pancreatic islets. Jpn. J. Physiol. 48(Suppl): S41
2 ) Kitamura, N., Ohta, T. and Nakazato, Y. 1998. N-type calcium channel is involved in depolarization-induced facilitation of calcium channel currents in porcine chromaffin cells. Naunyn-Schmiedeberg's Archives of Pharmacology Suppl. 2 358 No 1 R692
1997
Original articles
1 ) Tanaka, K., Shibuya, I., Nagatomo, T., Yamashita, H. and Kanno, T. 1996. Pituitary adenylate cyclase-activating polypeptide causes rapid Ca2+ release from intracellular stores and long lasting Ca2+ influx mediated by Na+ influx-dependent membrane depolarization in bovine adrenal chromaffin cells. Endocrinology, 137(3): 956-966.
2 ) Satoh, Y., Gesase, A. P., Habara, Y., Ono, K. and Kanno, T. 1996. Lipid secretory mechanisms in the mammalian Harderian gland. Microsc. Res. Tech., 34:104-110
3 ) Satoh, Y., Sano. K., Habara, Y. and Kanno, T. 1997. Effects of carbachol and catecholamines on ultrastructure and intracellular calcium ion dynamics of acinar and myoepithelial cells of lacrimal glands. Cell Tissue Res., 289: 473-485
4 ) Cui, Z.J. and Kanno, T. 1997. Photodynamic triggering of calcium oscillation in the isolated rat pancreatic acini. Journal of Physiology, 504(1):47-55
5 ) Maruyama, T., Cui, Z.J., Kanaji, T., Mikoshiba, K. and Kanno T. 1997. Attenuation of intracellular Ca2+ and secretory responses by ins(1,4,5)P-3-induced Ca2+ release modulator, 2APB, in rat pancreatic acinar cells. Biomedical Research, 18(4):297-302.
Publication other than original articles
1 ) Kanno, T., Asada, N. and Habara, Y. 1996. Characteristics of Ca2+ signalling in adriamycin-sensitive or resistant cell lines of human lung cancer, SBC-3. Jpn. J. Physiol., 46(suppl) S10
2 ) Asada, N., Iwanaga, T., Shibuya, I., Niwa, K. and Kanno, T. 1996. Analysis of Ca2+ responses in islet cells, identification of A cell and B cell. Jpn. J. Physiol., 46(suppl.) S23
3 ) Tanaka, K., Shibuya, I. and Kanno, T. 1996. Mechanisms of PACAP-induced [Ca2+]i increase in bovine adrenal chromaffin cells. Jpn. J. Physiol., 46(suppl.) S25
1996
Original articles
1 ) Habara, Y., Nakamura R., Sakaguchi, K., Satoh, Y. and Kanno, T. 1996. Ratiometric imaging of [Ca2+]i dynamics by UV-laser scanning confocal microscopy in indo-1-loaded rat pancreatic acinus. Biomedical Research, 17: 27-34.
2 ) Kanno, T., Asada, N., Habara, Y., Ishida, T., Saijo, N. and Abe, K. 1996. Differentiation of Ca2+ signalling between adriamycin-sensitive and resistant cell lines of human lung cancer, SBC-3. Biomedical Research, 17: 81-86.
3 ) Habara, Y. and Kanno, T. 1996. Perimetric [Ca2+]i rise and exocytosis detected by ultraviolet laser scanning confocal microscopy in rat peritoneal mast cells. Experimental Physiology, 81: 319-328.
4 ) Kanno, T., Asada, N. and Niwa, K. 1996. Coordination in oscillatory Ca+ sigmalling in islet and acinar cells in mouse pancreas. In: Studies in Honour of John Atherton Young, pp. 149-154. Univ. Sydney Printing Service, Australia.
5 ) Busik, J., Nakamura, M., Abe, Y., Shibuya, I. and Kanno, T. 1996. Effects of GABA on spontaneous [Ca2+]c dynamics and electrical properties of rat adrenal chromaffin cells. Brain Research, 739: 97-103.
6 ) Yoshihashi, K., Shibuya, I. and Kanno, T. 1996 Contribution of Na+ / Ca2+ exchanger in maintaining [Ca2+]c at a stable state in rat pancreatic islets. Japnanese~ournal of Physiotogy, 46: 473-480.
7 ) Ohno, H., Habara, Y., Kizaki, T., Oh-ishi, S., Tanaka, J. and Gasa, S. 1996. Increased growth of brown adipose tissue but its decreased Iysosomal enzyme activity in heat-acclimatized, insulin-treated rats. Horm. Metab. Res., 28: 397-399.
8 ) Ohno, H., Tanaka, J., Habara, Y., Uehara, Y., Kizaki, T., Oh-ishi, S., Fukuda, K. and Gasa, S. 1996. Effects of acute or chronic exposure to cold on the Iysosomal enzyme system in rat tissues. Pathophysiol. 3:181-185.
9 ) Cui, Z. J., Habara, Y., Wang, D. Y. and Kanno T. 1997. A novel aspect of photodynamic action.: Induction of recurrent spikes in cytosolic calcium concentration. Photochemistry and Photobiology, 65: 382-386.
Publications other than original articles
1 ) Shinozaki, H., Abe, Y., Miyasaka, K., Funahoshi, A. 1996. Effect of UESODEOXYCHOLATE (UDCA) on chlecystokinin (CCK) and CCK-JMV-180 stimulated pancreatic exocrine secretion in in vitro study. In: Proceedings of The Seventeen Gut Hormone Conference, 17, pp. 138-141 (in Japanese).
2 ) Nishimori, K. and Kanno, T. 1996. An analysis of synergistic of PACAP-38 on CCK-8-induced secretory response in the exocrine pancreas of rat. ibid, pp. 132-136 (in Japanese).